In a neural circuit, synapses transfer information rapidly between neurons and transform this
information during transfer. The diverse computational properties of synapses are shaped by …

The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of
juvenile rat. The reconstruction uses cellular and synaptic organizing principles to …

Action potentials trigger neurotransmitter release at the presynaptic active zone with
spatiotemporal precision. This is supported by protein machinery that mediates synaptic …

Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …

Due to the increasing importance of artificial intelligence (AI), significant recent effort has
been devoted to the development of neuromorphic circuits that seek to emulate the energy …

Memristors have attracted broad interest as a promising candidate for future memory and
computing applications. Particularly, it is believed that memristors can effectively implement …

Somatostatin-expressing GABAergic neurons constitute a major class of inhibitory neurons
in the mammalian cortex and are characterized by dense wiring into the local network and …

▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and
wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic …

Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions
that are supported by the neocortex. The neocortex, which forms almost 80% of the human …