Interleukin 11 (IL11) is an elusive member of the IL6 family of cytokines. While initially
thought to be a haematopoietic and cytoprotective factor, more recent data show instead that …

Interleukin-11 is a cytokine from the IL-6 family of cytokines that includes IL-6 and oncostatin-
M. Initially described for its role in platelet generation, it is now appreciated that this cytokine …

SARS-CoV-19 infection provokes a variety of symptoms; most patients present
mild/moderate symptoms, whereas a small proportion of patients progress to severe illness …

Antiviral signaling, immune response and cell metabolism are dysregulated by SARS‐CoV‐
2, the causative agent of COVID‐19. Here, we show that SARS‐CoV‐2 accessory proteins …

Background SARS-CoV-2 infection is considered as a relapsing inflammatory process with a
dysregulation of IL-6 signalling. Classic IL-6 signalling is thought to represent a defence …

Introduction Serum levels of interleukin-6 (IL-6) are increased in COVID-19 patients. IL-6 is
an effective therapeutic target in inflammatory diseases and tocilizumab, a monoclonal …

The outbreak of COVID-19, led to an ongoing pandemic with devastating consequences for
the global economy and human health. With the global spread of SARS-CoV-2 …

As the final stage of disease‐related tissue injury and repair, fibrosis is characterized by
excessive accumulation of the extracellular matrix. Unrestricted accumulation of stromal …

Viral accessory proteins play critical roles in viral escape from host innate immune
responses and in viral inflammatory pathogenesis. Here we show that the SARS‐CoV‐2 …

The study presents data on the anti-inflammatory effects of a combination of sodium
dichloroacetate and sodium valproate (DCA–VPA) on the expression of inflammation-and …