What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP's prognostic ability in different cancer types

CM Farag, R Antar, S Akosman, M Ng… - Oncotarget, 2023 - pmc.ncbi.nlm.nih.gov
Since its inception, the Hemoglobin, Albumin, Lymphocyte, Platelet Score (HALP) has
gained attention as a new prognostic biomarker to predict several clinical outcomes in a …

[HTML][HTML] PD-L1 testing for lung cancer in 2019: perspective from the IASLC pathology committee

S Lantuejoul, M Sound-Tsao, WA Cooper… - Journal of Thoracic …, 2020 - Elsevier
The recent development of immune checkpoint inhibitors (ICIs) has led to promising
advances in the treatment of patients with NSCLC and SCLC with advanced or metastatic …

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

H Weng, F Huang, Z Yu, Z Chen, E Prince, Y Kang… - Cancer cell, 2022 - cell.com
Summary N 6-Methyladenosine (m 6 A) modification and its modulators play critical roles
and show promise as therapeutic targets in human cancers, including acute myeloid …

[HTML][HTML] Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma

L Dong, D Lu, R Chen, Y Lin, H Zhu, Z Zhang, S Cai… - Cancer cell, 2022 - cell.com
We performed proteogenomic characterization of intrahepatic cholangiocarcinoma (iCCA)
using paired tumor and adjacent liver tissues from 262 patients. Integrated proteogenomic …

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

X Chen, A Li, BF Sun, Y Yang, YN Han, X Yuan… - Nature cell …, 2019 - nature.com
Abstract Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its
regulation and biological role in pathological conditions (such as cancer) remain unknown …

A nomogram for predicting overall survival in patients with low‐grade endometrial stromal sarcoma: A population‐based analysis

J Wu, H Zhang, L Li, M Hu, L Chen, B Xu… - Cancer …, 2020 - Wiley Online Library
Background Low‐grade endometrial stromal sarcoma (LG‐ESS) is a rare tumor that lacks a
prognostic prediction model. Our study aimed to develop a nomogram to predict overall …

[HTML][HTML] aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis

R Fan, G Papatheodoridis, J Sun, H Innes… - Journal of …, 2020 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is the leading cause of death in
patients with chronic hepatitis. In this international collaboration, we sought to develop a …

TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

Y Li, M Xue, X Deng, L Dong, L Ren, L Han, C Li, J Xue… - Cell Stem Cell, 2023 - cell.com
TET2 is recurrently mutated in acute myeloid leukemia (AML) and its deficiency promotes
leukemogenesis (driven by aggressive oncogenic mutations) and enhances leukemia stem …

Association of intratumoral microbiota with prognosis in patients with nasopharyngeal carcinoma from 2 hospitals in China

H Qiao, XR Tan, H Li, JY Li, XZ Chen, YQ Li… - JAMA …, 2022 - jamanetwork.com
Importance Microbiota-tumor interactions have qualified microbiota as a promising
prognostic biomarker in various types of cancers. Although the nasopharynx acts as a …

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment

HQ Dinh, F Pan, G Wang, QF Huang, CE Olingy… - Nature …, 2021 - nature.com
The tumor microenvironment is a highly complex ecosystem of diverse cell types, which
shape cancer biology and impact the responsiveness to therapy. Here, we analyze the …