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What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP's prognostic ability in different cancer types
Since its inception, the Hemoglobin, Albumin, Lymphocyte, Platelet Score (HALP) has
gained attention as a new prognostic biomarker to predict several clinical outcomes in a …
gained attention as a new prognostic biomarker to predict several clinical outcomes in a …
[HTML][HTML] PD-L1 testing for lung cancer in 2019: perspective from the IASLC pathology committee
The recent development of immune checkpoint inhibitors (ICIs) has led to promising
advances in the treatment of patients with NSCLC and SCLC with advanced or metastatic …
advances in the treatment of patients with NSCLC and SCLC with advanced or metastatic …
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
Summary N 6-Methyladenosine (m 6 A) modification and its modulators play critical roles
and show promise as therapeutic targets in human cancers, including acute myeloid …
and show promise as therapeutic targets in human cancers, including acute myeloid …
[HTML][HTML] Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma
We performed proteogenomic characterization of intrahepatic cholangiocarcinoma (iCCA)
using paired tumor and adjacent liver tissues from 262 patients. Integrated proteogenomic …
using paired tumor and adjacent liver tissues from 262 patients. Integrated proteogenomic …
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
X Chen, A Li, BF Sun, Y Yang, YN Han, X Yuan… - Nature cell …, 2019 - nature.com
Abstract Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its
regulation and biological role in pathological conditions (such as cancer) remain unknown …
regulation and biological role in pathological conditions (such as cancer) remain unknown …
A nomogram for predicting overall survival in patients with low‐grade endometrial stromal sarcoma: A population‐based analysis
J Wu, H Zhang, L Li, M Hu, L Chen, B Xu… - Cancer …, 2020 - Wiley Online Library
Background Low‐grade endometrial stromal sarcoma (LG‐ESS) is a rare tumor that lacks a
prognostic prediction model. Our study aimed to develop a nomogram to predict overall …
prognostic prediction model. Our study aimed to develop a nomogram to predict overall …
[HTML][HTML] aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis
Background & Aims Hepatocellular carcinoma (HCC) is the leading cause of death in
patients with chronic hepatitis. In this international collaboration, we sought to develop a …
patients with chronic hepatitis. In this international collaboration, we sought to develop a …
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
TET2 is recurrently mutated in acute myeloid leukemia (AML) and its deficiency promotes
leukemogenesis (driven by aggressive oncogenic mutations) and enhances leukemia stem …
leukemogenesis (driven by aggressive oncogenic mutations) and enhances leukemia stem …
Association of intratumoral microbiota with prognosis in patients with nasopharyngeal carcinoma from 2 hospitals in China
H Qiao, XR Tan, H Li, JY Li, XZ Chen, YQ Li… - JAMA …, 2022 - jamanetwork.com
Importance Microbiota-tumor interactions have qualified microbiota as a promising
prognostic biomarker in various types of cancers. Although the nasopharynx acts as a …
prognostic biomarker in various types of cancers. Although the nasopharynx acts as a …
Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment
The tumor microenvironment is a highly complex ecosystem of diverse cell types, which
shape cancer biology and impact the responsiveness to therapy. Here, we analyze the …
shape cancer biology and impact the responsiveness to therapy. Here, we analyze the …