Small and long non-coding RNAs: Past, present, and future
LL Chen, VN Kim - Cell, 2024 - cell.com
Since the introduction of the central dogma of molecular biology in 1958, various RNA
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …
The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches
AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …
support of clinical-pathological data such as the sum of the Gleason score and serum levels …
The role of non-coding RNAs in glioma
For decades, research in cancer biology has been focused on the protein-coding fraction of
the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has …
the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has …
The metabolism-related lncRNA signature predicts the prognosis of breast cancer patients
X Ge, S Lei, P Wang, W Wang, W Wang - Scientific Reports, 2024 - nature.com
Long non-coding RNAs (lncRNAs) involved in metabolism are recognized as significant
factors in breast cancer (BC) progression. We constructed a novel prognostic signature for …
factors in breast cancer (BC) progression. We constructed a novel prognostic signature for …
[HTML][HTML] Current advancements and future perspectives of long noncoding RNAs in lipid metabolism and signaling
Background The investigation of lncRNAs has provided a novel perspective for elucidating
mechanisms underlying diverse physiological and pathological processes. Compelling …
mechanisms underlying diverse physiological and pathological processes. Compelling …
Risk score= LncRNAs associated with doxorubicin metabolism can be used as molecular markers for immune microenvironment and immunotherapy in non-small cell …
Q Lin, M Zhang, Y Kong, Z Huang, Z Zou, Z **ong… - Heliyon, 2023 - cell.com
Doxorubicin is the most effective anthracycline chemotherapy drug in the treatment of
cancer, and it is an effective single agent in the treatment of non-small cell lung cancer …
cancer, and it is an effective single agent in the treatment of non-small cell lung cancer …
Directional integration and pathway enrichment analysis for multi-omics data
Omics techniques generate comprehensive profiles of biomolecules in cells and tissues.
However, a holistic understanding of underlying systems requires joint analyses of multiple …
However, a holistic understanding of underlying systems requires joint analyses of multiple …
Pan-cancer ion transport signature reveals functional regulators of glioblastoma aggression
AT Bahcheli, HK Min, M Bayati, H Zhao… - The EMBO …, 2024 - embopress.org
Ion channels, transporters, and other ion-flux controlling proteins, collectively comprising the
“ion permeome”, are common drug targets, however, their roles in cancer remain …
“ion permeome”, are common drug targets, however, their roles in cancer remain …
A CRISPR path to finding vulnerabilities and solving drug resistance: Targeting the diverse cancer landscape and its ecosystem
B McLean, A Istadi, T Clack, M Vankan… - Advanced …, 2022 - Wiley Online Library
Cancer is the second leading cause of death globally, with therapeutic resistance being a
major cause of treatment failure in the clinic. The dynamic signaling that occurs between …
major cause of treatment failure in the clinic. The dynamic signaling that occurs between …
Tumour mutations in long noncoding RNAs enhance cell fitness
Long noncoding RNAs (lncRNAs) are linked to cancer via pathogenic changes in their
expression levels. Yet, it remains unclear whether lncRNAs can also impact tumour cell …
expression levels. Yet, it remains unclear whether lncRNAs can also impact tumour cell …