Bladder cancer accounts for nearly 170,000 deaths worldwide annually. For over 4 decades,
the systemic management of muscle‐invasive and advanced bladder cancer has primarily …

Neoadjuvant cisplatin-based chemotherapy (NACC) followed by radical cystectomy is the
standard treatment for localized muscle-invasive bladder cancer (MIBC). Patients who …

Background The purpose of this study was to assess patient frailty as a risk factor for radical
cystectomy (RC) complications. Materials and Methods We performed an analysis of …

Purpose: Half of patients with muscle-invasive bladder cancer worldwide may not receive
curative-intent therapy. Elderly or frail patients are most affected by this unmet need. TAR …

Introduction A modified 5-item frailty index was recently developed as a predictor of patient
comorbidity-based mortality and morbidity. We evaluate the association between …

Abstract Purpose of the Review This review targets the latest literature on bladder
preservation therapy with emphasis on trimodal therapy (TMT), highlighting its role in the …

Objectives To systematically review and meta-analyze the current literature in a
methodologically rigorous and transparent manner for quantitative evidence on survival …

Purpose To assess how trends in urinary diversion (UD) type following radical cystectomy
(RC) have changed in recent years and investigate pre-operative predictors of UD type …

Background Radical cystectomy (RC) is the standard treatment for bladder cancer, but the
safety and efficacy of this treatment for elderly people need to be considered. We compare …

Purpose To test the hypothesis that bladder preservation therapy consisting of definitive
chemoradiotherapy (chemo RT) results in similar overall survival rates to radical cystectomy …