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Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
[HTML][HTML] State of the nation in data integration for bioinformatics
Data integration is a perennial issue in bioinformatics, with many systems being developed
and many technologies offered as a panacea for its resolution. The fact that it is still a …
and many technologies offered as a panacea for its resolution. The fact that it is still a …
An introduction to ontology engineering
CM Keet - 2018 - open.uct.ac.za
Abstract An Introduction to Ontology Engineering is a free online textbook that provides an
overview of ontology engineering, including logics and automated reasoning, methods and …
overview of ontology engineering, including logics and automated reasoning, methods and …
myExperiment: social networking for workflow-using e-scientists
We present the Taverna workflow workbench and argue that scientific workflow
environments need a rich ecosystem of tools that support the scientists. experimental …
environments need a rich ecosystem of tools that support the scientists. experimental …
[PDF][PDF] Scientific Process Automation and Workflow Management.
We introduce and describe scientific workflows, ie, executable descriptions of automatable
scientific processes such as computational science simulations and data analyses. Scientific …
scientific processes such as computational science simulations and data analyses. Scientific …
[HTML][HTML] An ontology-driven semantic mashup of gene and biological pathway information: Application to the domain of nicotine dependence
OBJECTIVES: This paper illustrates how Semantic Web technologies (especially RDF, OWL,
and SPARQL) can support information integration and make it easy to create semantic …
and SPARQL) can support information integration and make it easy to create semantic …
Scientific discovery as a combinatorial optimisation problem: how best to navigate the landscape of possible experiments?
DB Kell - Bioessays, 2012 - Wiley Online Library
A considerable number of areas of bioscience, including gene and drug discovery,
metabolic engineering for the biotechnological improvement of organisms, and the …
metabolic engineering for the biotechnological improvement of organisms, and the …
Data curation+ process curation= data integration+ science
In bioinformatics, we are familiar with the idea of curated data as a prerequisite for data
integration. We neglect, often to our cost, the curation and cataloguing of the processes that …
integration. We neglect, often to our cost, the curation and cataloguing of the processes that …
The virtual human: towards a global systems biology of multiscale, distributed biochemical network models
DB Kell - IUBMB life, 2007 - Wiley Online Library
There is an emerging recognition of the importance of modelling large‐scale biochemical
systems, with the 'digital human'an obviously desirable goal. This will then permit …
systems, with the 'digital human'an obviously desirable goal. This will then permit …
Molecular Recognition at an Organic− Aqueous Interface: Heterocalixarenes as Anion Binding Agents in Liquid Polymeric Membrane Ion-Selective Electrodes
V Král, JL Sessler, TV Shishkanova… - Journal of the …, 1999 - ACS Publications
Poly (vinyl chloride)(PVC)-derived ion-selective electrodes (ISEs) have been prepared from
a neutral anion binding receptor, meso-octamethylcalix [4] pyrrole (1). Analogous systems …
a neutral anion binding receptor, meso-octamethylcalix [4] pyrrole (1). Analogous systems …