Multipotent stem cell and current application

A Sobhani, N Khanlarkhani, M Baazm… - Acta Medica …, 2017 - acta.tums.ac.ir
Stem cells are self-renewing and undifferentiated cell types that can be differentiate into
functional cells. Stem cells can be classified into two main types based on their source of …

Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review

R Zhankina, N Baghban, M Askarov… - Stem Cell Research & …, 2021 - Springer
Stem cells have been introduced as new promising therapeutic agents in treatment of
degenerative diseases because of having high differentiation potential while maintaining the …

Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model

F Madani, H Morovvati, TJ Webster, S Najaf Asaadi… - Scientific Reports, 2024 - nature.com
The effect of chemotherapy for anti-glioblastoma is limited due to insufficient drug delivery
across the blood–brain–barrier. Poloxamer 188-coated nanoparticles can enhance the …

Cisplatin-induced azoospermia and testicular damage ameliorated by adipose-derived mesenchymal stem cells

HY Ismail, NA Shaker, S Hussein, A Tohamy, M Fathi… - Biological Research, 2023 - Springer
Background The testes are highly susceptible to the adverse effects of chemotherapy and
radiation at all stages of life. Exposure to these threats mainly occurs during cancer …

Adipose tissue-derived mesenchymal stem cells repair germinal cells of seminiferous tubules of busulfan-induced azoospermic rats

D Mehrabani, MA Hassanshahi… - Journal of human …, 2015 - journals.lww.com
AIMS: The aims of this study were to evaluate the germinal cells characteristics and repairs
in seminiferous tubules of busulfan-induced azoospermic rats after AT-MSCs …

[HTML][HTML] Early intervention with breast milk mesenchymal stem cells attenuates the development of diabetic-induced testicular dysfunction via hypothalamic Kisspeptin …

T Khamis, AF Abdelalim, SH Abdallah… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Diabetic male infertility and sub fertility are major complications that may implicate both
central and peripheral pathways as well as mechanisms controlling reproduction. This study …

Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model

D Zhang, X Liu, J Peng, D He, T Lin, J Zhu, X Li… - International journal of …, 2014 - mdpi.com
Non-obstructive azoospermia is the most challenging type of male infertility. Stem cell based
therapy provides the potential to enhance the recovery of spermatogenesis following cancer …

Protective effect of L‐carnitine and L‐arginine against busulfan‐induced oligospermia in adult rat

AM Abd‐Elrazek, OAH Ahmed‐Farid - Andrologia, 2018 - Wiley Online Library
Busulfan is an anticancer drug caused variety of adverse effects for patients with cancer. But
it could cause damage to the male reproductive system as one of its adverse effects. This …

A pumpless monolayer microfluidic device based on mesenchymal stem cell-conditioned medium promotes neonatal mouse in vitro spermatogenesis

S Önen, AC Atik, M Gizer, S Köse, Ö Yaman… - Stem Cell Research & …, 2023 - Springer
Background Childhood cancer treatment-induced gonadotoxicity causes permanent
infertility/sub-infertility in nearly half of males. The current clinical and experimental …

Preventing/reversing adverse effects of endocrine disruption on mouse testes by normalizing tissue resident VSELs

A Kaushik, SM Metkari, S Ali, D Bhartiya - Stem Cell Reviews and Reports, 2023 - Springer
Reproductive health of men is declining in today's world due to increased developmental
exposure to endocrine-disrupting chemicals (EDCs). We earlier reported that neonatal …