Sensing internal bodily signals, or interoception, is fundamental to maintain life. However,
interoception should not be viewed as an isolated domain, as it interacts with exteroception …

Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

The term “salience network” refers to a suite of brain regions whose cortical hubs are the
anterior cingulate and ventral anterior insular (ie, frontoinsular) cortices. This network, which …

A century-long debate on bodily states and emotions persists. While the involvement of
bodily activity in emotion physiology is widely recognized, the specificity and causal role of …

Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

Abstract Several models propose Motor Imagery, Action Observation, and Movement
Execution recruit the same brain regions. There is, however, no quantitative synthesis of the …

Studies show that the autonomic nervous system (ANS) has an important impact on health in
general. In response to environmental demands, homeostatic processes are often …

Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other
symptoms, and has a substantial socioeconomic impact. Current biomedical and …

After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …

Most research in cognitive neuroscience explores how external stimuli are processed by the
brain. However, the brain also receives input from the internal body. We discuss here how …