Thiamine and benfotiamine: Focus on their therapeutic potential

I Bozic, I Lavrnja - Heliyon, 2023 - cell.com
Thiamine, also known as vitamin B1, is an essential nutrient that plays a crucial role in
energy metabolism and overall health. It is a water-soluble vitamin that plays an important …

Revisiting the role of vitamins and minerals in Alzheimer's disease

H Shah, F Dehghani, M Ramezan, RB Gannaban… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia that affects millions of
individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized …

Neuroprotective potential of Honokiol in ICV-STZ induced neuroinflammation, Aβ (1− 4 2) and NF-kB expression in experimental model of rats

L Singh, S Singh - Neuroscience letters, 2023 - Elsevier
Alzheimer's disease (AD) is a most common and prevalent age related insidious
neurological condition characterised by formation of Aβ (1− 4 2) plaques and NFT in the …

Altered secretion, constitution, and functional properties of the gastrointestinal mucus in a rat model of sporadic alzheimer's disease

J Homolak, J De Busscher… - ACS Chemical …, 2023 - ACS Publications
The gastrointestinal (GI) system is affected in Alzheimer's disease (AD); however, it is
currently unknown whether GI alterations arise as a consequence of central nervous system …

Benfotiamine attenuates the high-carbohydrate diet-induced mitochondrial redox imbalance in fish Megalobrama amblycephala by activating SIRT3

L Zhang, YP Ge, YY Huang, WL Chen, WB Liu… - Aquaculture, 2023 - Elsevier
Fish are carbohydrates-intolerant, thus generally exhibiting metabolic disorders and
mitochondrial dysfunctions to high-carbohydrate (HC) diets. Benfotiamine is a lipid-soluble …

Insights into Gastrointestinal Redox Dysregulation in a Rat Model of Alzheimer's Disease and the Assessment of the Protective Potential of D-galactose

J Homolak, K Varvaras, V Sciacca, A Babic Perhoc… - ACS …, 2024 - ACS Publications
Recent evidence suggests that the gut plays a vital role in the development and progression
of Alzheimer's disease (AD) by triggering systemic inflammation and oxidative stress. The …

Exploring the Therapeutic Potential of Benfotiamine in a Sporadic Alzheimer's-Like Disease Rat Model: Insights into Insulin Signaling and Cognitive function

CAEF Cardinali, YA Martins, RCM Moraes… - ACS Chemical …, 2024 - ACS Publications
Alzheimer's disease (AD) is a complex neurodegenerative process, also considered a
metabolic condition due to alterations in glucose metabolism and insulin signaling pathways …

[HTML][HTML] Searching for new drugs to treat Alzheimer's disease dementia through multiple pathways

H Bai, XF Feng - World Journal of Clinical Cases, 2025 - pmc.ncbi.nlm.nih.gov
Dementia is a group of diseases, including Alzheimer's disease (AD), vascular dementia,
Lewy body dementia, frontotemporal dementia, Parkinson's disease dementia, metabolic …

Thiamine and benfotiamine: Focus on their therapeutic potential

I Bozic, I Lavrnja - europepmc.org
Thiamine, also known as vitamin B1, is an essential nutrient that plays a crucial role in
energy metabolism and overall health. It is a water-soluble vitamin that plays an important …