A field guide to eukaryotic transposable elements

JN Wells, C Feschotte - Annual review of genetics, 2020 - annualreviews.org
Transposable elements (TEs) are mobile DNA sequences that propagate within genomes.
Through diverse invasion strategies, TEs have come to occupy a substantial fraction of …

Origins and evolution of CRISPR-Cas systems

EV Koonin, KS Makarova - Philosophical Transactions of …, 2019 - royalsocietypublishing.org
CRISPR-Cas, the bacterial and archaeal adaptive immunity systems, encompass a complex
machinery that integrates fragments of foreign nucleic acids, mostly from mobile genetic …

Insights into mammalian TE diversity through the curation of 248 genome assemblies

AB Osmanski, NS Paulat, J Korstian, JR Grimshaw… - Science, 2023 - science.org
We examined transposable element (TE) content of 248 placental mammal genome
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …

Evolutionary entanglement of mobile genetic elements and host defence systems: guns for hire

EV Koonin, KS Makarova, YI Wolf… - Nature Reviews …, 2020 - nature.com
All cellular life forms are afflicted by diverse genetic parasites, including viruses and other
types of mobile genetic elements (MGEs), and have evolved multiple, diverse defence …

Large-scale invasion of unicellular eukaryotic genomes by integrating DNA viruses

C Bellas, T Hackl, MS Plakolb, A Koslová… - Proceedings of the …, 2023 - pnas.org
Eukaryotic genomes contain a variety of endogenous viral elements (EVEs), which are
mostly derived from RNA and ssDNA viruses that are no longer functional and are …

Evolution and diversity of transposable elements in vertebrate genomes

CG Sotero-Caio, RN Platt, A Suh… - Genome biology and …, 2017 - academic.oup.com
Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via
transposition or retrotransposition and often make up large fractions of vertebrate genomes …

A unified classification system for eukaryotic transposable elements

T Wicker, F Sabot, A Hua-Van, JL Bennetzen… - Nature reviews …, 2007 - nature.com
Our knowledge of the structure and composition of genomes is rapidly progressing in pace
with their sequencing. The emerging data show that a significant portion of eukaryotic …

Endogenous virophages are active and mitigate giant virus infection in the marine protist Cafeteria burkhardae

A Koslová, T Hackl, F Bade… - Proceedings of the …, 2024 - pnas.org
Endogenous viral elements (EVEs) are common genetic passengers in various protists.
Some EVEs represent viral fossils, whereas others are still active. The marine heterotrophic …

DNA transposons and the evolution of eukaryotic genomes

C Feschotte, EJ Pritham - Annu. Rev. Genet., 2007 - annualreviews.org
Transposable elements are mobile genetic units that exhibit broad diversity in their structure
and transposition mechanisms. Transposable elements occupy a large fraction of many …

Viruses defined by the position of the virosphere within the replicator space

EV Koonin, VV Dolja, M Krupovic… - … and Molecular Biology …, 2021 - journals.asm.org
Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …