Tryptophan metabolic pathways and brain serotonergic activity: a comparative review

E Höglund, Ø Øverli, S Winberg - Frontiers in endocrinology, 2019 - frontiersin.org
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic
neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Numerous studies have shown that …

Effects of waterborne antidepressants on non-target animals living in the aquatic environment: a review

P Sehonova, Z Svobodova, P Dolezelova… - Science of the Total …, 2018 - Elsevier
After application, antidepressants, like other pharmaceuticals, are excreted from human
body in their native form or as metabolites and enter the aquatic environment via different …

Effluent from drug manufactures contains extremely high levels of pharmaceuticals

DGJ Larsson, C de Pedro, N Paxeus - Journal of hazardous materials, 2007 - Elsevier
It is generally accepted that the main route for human pharmaceuticals to the aquatic
environment is via sewage treatment plants receiving wastewater from households and …

The potential for adverse effects in fish exposed to antidepressants in the aquatic environment

SL Gould, MJ Winter, WHJ Norton… - Environmental science & …, 2021 - ACS Publications
Antidepressants are one of the most commonly prescribed pharmaceutical classes for the
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …

Evolutionary background for stress-co** styles: relationships between physiological, behavioral, and cognitive traits in non-mammalian vertebrates

Ø Øverli, C Sørensen, KGT Pulman, TG Pottinger… - Neuroscience & …, 2007 - Elsevier
Reactions to stress vary between individuals, and physiological and behavioral responses
tend to be associated in distinct suites of correlated traits, often termed stress-co** styles …

The use of dietary additives in fish stress mitigation: Comparative endocrine and physiological responses

M Herrera, JM Mancera, B Costas - Frontiers in endocrinology, 2019 - frontiersin.org
In the last years, studies on stress attenuation in fish have progressively grown. This is
mainly due to the interest of institutions, producers, aquarists and consumers in improving …

Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish

M Galus, N Kirischian, S Higgins, J Purdy, J Chow… - Aquatic toxicology, 2013 - Elsevier
Pharmaceuticals are found in both receiving and drinking water due to their persistent
release in waste-water effluents, raising concerns for environmental and human health …

Plasticity in animal personality traits: does prior experience alter the degree of boldness?

AJ Frost, A Winrow-Giffen… - Proceedings of the …, 2007 - royalsocietypublishing.org
Theoreticians predict that animal 'personality'traits may be maladaptive if fixed throughout
different contexts, so the present study aimed to test whether these traits are fixed or plastic …

Physiological roles of tryptophan in teleosts: current knowledge and perspectives for future studies

SM Hoseini, A Pérez‐Jiménez, B Costas… - Reviews in …, 2019 - Wiley Online Library
Tryptophan is an essential amino acid with a huge functional versatility, in addition to its
participation in protein synthesis. Because of the complexity of its metabolism, and the …

Pharmaceuticals as neuroendocrine disruptors: lessons learned from fish on Prozac

JA Mennigen, P Stroud, JM Zamora… - Journal of Toxicology …, 2011 - Taylor & Francis
Pharmaceuticals are increasingly detected in a variety of aquatic systems. One of the most
prevalent environmental pharmaceuticals in North America and Europe is the …