SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact

M Lipsitch, F Krammer, G Regev-Yochay… - Nature Reviews …, 2022 - nature.com
Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …

Theoretical framework for retrospective studies of the effectiveness of SARS-CoV-2 vaccines

JA Lewnard, MM Patel, NP Jewell, JR Verani… - …, 2021 - journals.lww.com
Observational studies of the effectiveness of vaccines to prevent COVID-19 are needed to
inform real-world use. Such studies are now underway amid the ongoing rollout of SARS …

Association between 3 doses of mRNA COVID-19 vaccine and symptomatic infection caused by the SARS-CoV-2 Omicron and Delta variants

EK Accorsi, A Britton, KE Fleming-Dutra, ZR Smith… - Jama, 2022 - jamanetwork.com
Importance Assessing COVID-19 vaccine performance against the rapidly spreading SARS-
CoV-2 Omicron variant is critical to inform public health guidance. Objective To estimate the …

Maternal vaccination and risk of hospitalization for Covid-19 among infants

NB Halasa, SM Olson, MA Staat… - … England Journal of …, 2022 - Mass Medical Soc
Background Infants younger than 6 months of age are at high risk for complications of
coronavirus disease 2019 (Covid-19) and are not eligible for vaccination. Transplacental …

Effectiveness of Covid-19 vaccines in ambulatory and inpatient care settings

MG Thompson, E Stenehjem, S Grannis… - … England Journal of …, 2021 - Mass Medical Soc
Background There are limited data on the effectiveness of the vaccines against symptomatic
coronavirus disease 2019 (Covid-19) currently authorized in the United States with respect …

BNT162b2 protection against the omicron variant in children and adolescents

AM Price, SM Olson, MM Newhams… - … England Journal of …, 2022 - Mass Medical Soc
Background Spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
B. 1.1. 529 (omicron) variant, which led to increased US hospitalizations for coronavirus …

Effectiveness of BNT162b2 vaccine against critical Covid-19 in adolescents

SM Olson, MM Newhams, NB Halasa… - … England Journal of …, 2022 - Mass Medical Soc
Background The increasing incidence of pediatric hospitalizations associated with
coronavirus disease 2019 (Covid-19) caused by the B. 1.617. 2 (delta) variant of severe …

Understanding COVID-19 vaccine efficacy

M Lipsitch, NE Dean - Science, 2020 - science.org
The elderly and people with comorbidities are at greatest risk of severe coronavirus disease
2019 (COVID-19). A safe and effective vaccine could help to protect these groups in two …

Association of prior BNT162b2 COVID-19 vaccination with symptomatic SARS-CoV-2 infection in children and adolescents during omicron predominance

KE Fleming-Dutra, A Britton, N Shang, G Derado… - Jama, 2022 - jamanetwork.com
Importance Efficacy of 2 doses of the BNT162b2 COVID-19 vaccine (Pfizer-BioNTech)
against COVID-19 was high in pediatric trials conducted before the SARS-CoV-2 Omicron …

[HTML][HTML] Covid-19 vaccine effectiveness and the test-negative design

NE Dean, JW Hogan, ME Schnitzer - New England Journal of …, 2021 - Mass Medical Soc
Observational studies are emerging as fundamental sources of information about vaccine
effectiveness outside the controlled environment of randomized trials, and they are being …