Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

Most patients with pancreatic adenocarcinoma (PDAC) suffer cachexia; some do not. To
model heterogeneity, we used patient-derived orthotopic xenografts. These phenocopied …

Cancer cachexia (Ccx) is a complex metabolic condition characterized by pronounced
muscle and fat wasting, systemic inflammation, weakness and fatigue. Up to 30% of cancer …

Cachexia is a major cause of morbidity and mortality in individuals with cancer and is
characterized by weight loss due to adipose and muscle tissue wasting. Hallmarks of white …

Background: Numerous studies have shown that infiltrating eosinophils play a key role in the
tumor progression of bladder urothelial carcinoma (BLCA). However, the roles of …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and extremely therapy-resistant
cancer. It is estimated that up to 80% of PDAC patients present with cachexia, a multifactorial …

The study of the cellular secretome using proteomic techniques continues to capture the
attention of the research community across a broad range of topics in biomedical research …

Sarcopenia is an age-related geriatric syndrome characterized by the gradual loss of muscle
mass and function. Low-magnitude high-frequency vibration (LMHFV) was shown to be …

The progression of cancer from localized to metastatic disease is the primary cause of
morbidity and mortality. The interplay between the tumor and its microenvironment is the key …