A review on exosomes application in clinical trials: perspective, questions, and challenges
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …
communication. They convey active biomolecules to target cells and have vital functions in …
Exosomes as a new frontier of cancer liquid biopsy
D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
Exosome-based immunotherapy: a promising approach for cancer treatment
Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …
in the application of cell-released small vesicles that stimulate the immune system. As cell …
Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle
X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …
multistep endocytosis process and carry diverse functional molecular cargoes, including …
[HTML][HTML] Progress, opportunity, and perspective on exosome isolation-efforts for efficient exosome-based theranostics
D Yang, W Zhang, H Zhang, F Zhang, L Chen, L Ma… - Theranostics, 2020 - ncbi.nlm.nih.gov
Exosomes are small extracellular vesicles with diameters of 30-150 nm. In both
physiological and pathological conditions, nearly all types of cells can release exosomes …
physiological and pathological conditions, nearly all types of cells can release exosomes …
Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
ABSTRACT KRAS is the most frequently mutated oncogene in human neoplasia. Despite a
large investment to understand the effects of KRAS mutation in cancer cells, the direct effects …
large investment to understand the effects of KRAS mutation in cancer cells, the direct effects …
Technologies and standardization in research on extracellular vesicles
Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …
Challenges in the development and establishment of exosome-based drug delivery systems
J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small …
Small extracellular vesicles (sEVs) provide major promise for advances in cancer
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …