Cell type evolution reconstruction across species through cell phylogenies of single-cell RNA sequencing data

JL Mah, CW Dunn - Nature Ecology & Evolution, 2024 - nature.com
The origin and evolution of cell types has emerged as a key topic in evolutionary biology.
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …

Updated single cell reference atlas for the starlet anemone Nematostella vectensis

AG Cole, J Steger, J Hagauer, A Denner… - Frontiers in …, 2024 - Springer
Background The recent combination of genomics and single cell transcriptomics has
allowed to assess a variety of non-conventional model organisms in much more depth …

Acquisition of polymorphism in the chordate doliolids

CJ Pickett, J Ryan, B Davidson - Integrative and Comparative …, 2024 - academic.oup.com
In polymorphic organisms, a single genome is deployed to program numerous,
morphologically distinct body plans within a colony. This complex life history trait has …

Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and cnidarian …

D Thiel, LAY Guerra, A Kieswetter, AG Cole… - Elife, 2024 - elifesciences.org
Neuropeptides are ancient signaling molecules in animals but only few peptide receptors
are known outside bilaterians. Cnidarians possess a large number of G protein-coupled …

Evolutionary origin of the chordate nervous system revealed by amphioxus developmental trajectories

Y Dai, Y Zhong, R Pan, L Yuan, Y Fu, Y Chen… - Nature Ecology & …, 2024 - nature.com
The common ancestor of all vertebrates had a highly sophisticated nervous system, but
questions remain about the evolution of vertebrate neural cell types. The amphioxus, a …

Gene regulatory network that shaped the evolution of larval apical organ in Cnidaria

E Gilbert, J Craggs, V Modepalli - Molecular Biology and …, 2024 - academic.oup.com
Among non-bilaterian animals, a larval apical sensory organ with integrated neurons is only
found in cnidarians. Within cnidarians, an apical organ with a ciliary tuft is mainly found in …

An ancient apical patterning system sets the position of the forebrain in chordates

G Gattoni, D Keitley, A Sawle, E Benito-Gutiérrez - Science Advances, 2025 - science.org
The evolutionary origin of the vertebrate brain remains a major subject of debate, as its
development from a dorsal tubular neuroepithelium is unique to chordates. To shed light on …

An ancient gene regulatory network sets the position of the forebrain in chordates

G Gattoni, D Keitley, A Sawle, E Benito-Gutiérrez - BioRxiv, 2023 - biorxiv.org
The evolutionary origin of the vertebrate brain is still a major subject of debate. Its distinctive
dorsal position and development from a tubular neuroepithelium are unique to the chordate …

[HTML][HTML] Graded FGF activity patterns distinct cell types within the apical sensory organ of the sea anemone Nematostella vectensis

KZ Sabin, S Chen, EM Hill, KJ Weaver, J Yonke… - Developmental …, 2024 - Elsevier
Bilaterian animals have evolved complex sensory organs comprised of distinct cell types
that function coordinately to sense the environment. Each sensory unit has a defined …

Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata

JF Warner, R Besemer, A Schickle, E Borbee… - …, 2023 - pmc.ncbi.nlm.nih.gov
Cnidarians have become valuable models for understanding many aspects of
developmental biology including the evolution of body plan diversity, novel cell type …