Antibiotics have made it possible to treat bacterial infections such as meningitis and
bacteraemia that, prior to their introduction, were untreatable and consequently fatal …

Antibiotic resistance has become an indispensably alarming menace to the global
community. The primary factors are overuse and abuse of antibiotics, lack of novel …

Antimicrobial resistance (AMR) is a major public health problem that requires publicly
available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the …

After the first aminoglycoside antibiotic streptomycin being applied in clinical practice in the
mid-1940s, aminoglycoside antibiotics (AGAs) are widely used to treat clinical bacterial …

Aminoglycoside (AG) antibiotics are used to treat many Gram-negative and some Gram-
positive infections and, importantly, multidrug-resistant tuberculosis. Among various …

Acinetobacter baumannii is a common cause of serious nosocomial infections. Although
community-acquired infections are observed, the vast majority occur in people with …

Aminoglycosides are a group of antibiotics used since the 1940s to primarily treat a broad
spectrum of bacterial infections. The primary resistance mechanism against these antibiotics …

Antibiotics represent one of the most successful forms of therapy in medicine. But the
efficiency of antibiotics is compromised by a growing number of antibiotic-resistant …

History shows that the discovery of, and the resistance to, antibiotics go hand in hand. While
knowledge of resistance mechanisms, their impact and distribution is vast, over the years …

The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …