Importance Despite increasing emphasis on conservative management of patent ductus
arteriosus (PDA) in preterm infants, different pharmacotherapeutic interventions are used to …

Although a moderate-sized patent ductus arteriosus (PDA) needs to be closed by the time a
child is 1-2 years old, there is great uncertainty about whether it needs to be closed during …

Germinal matrix–intraventricular hemorrhage (GMH-IVH) is the most common variety of
neonatal intracranial hemorrhage and is characteristic of the premature infant. This form of …

Background Indomethacin is used as standard therapy to close a patent ductus arteriosus
(PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo …

Medical and surgical interventions are widely used to close a persistently patent ductus
arteriosus in preterm infants. Objective evidence to support these practices is lacking …

Background Patent ductus arteriosus (PDA) complicates the clinical course of preterm
infants and increases the risk of adverse outcomes. Indomethacin has been the standard …

Background Indomethacin is used as standard therapy to close a patent ductus arteriosus
(PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo …

Background A patent ductus arteriosus (PDA) with significant left to right shunt increases
morbidity and mortality in preterm infants. Early closure of the ductus arteriosus may be …

The patent ductus arteriosus (PDA) is the most commonly found cardiac condition in
neonates. While there have been several studies and thousands of publications on the topic …

OBJECTIVES. A hemodynamically important patent ductus arteriosus is a common problem
in the first week of life in the preterm infant. Although patent ductus arteriosus induces …