Matrix metalloproteinases as novel biomarker s and potential therapeutic targets in human cancer

R Roy, J Yang, MA Moses - Journal of clinical oncology, 2009 - ascopubs.org
The matrix metalloproteinase (MMP) family of enzymes is comprised of critically important
extracellular matrix remodeling proteases whose activity has been implicated in a number of …

The role of matrix metalloproteinases in colorectal cancer

AH Said, JP Raufman, G **e - Cancers, 2014 - mdpi.com
In the United States, colorectal cancer (CRC) is the third leading cause of cancer mortality,
with limited treatment options for those with advanced disease. Matrix metalloproteinases …

The immunomodulatory role of matrix metalloproteinases in colitis-associated cancer

L He, Q Kang, KI Chan, Y Zhang, Z Zhong… - Frontiers in …, 2023 - frontiersin.org
Matrix metalloproteinases (MMPs) are an important class of enzymes in the body that
function through the extracellular matrix (ECM). They are involved in diverse …

Geometrically encoded SERS nanobarcodes for the logical detection of nasopharyngeal carcinoma-related progression biomarkers

D Lin, CL Hsieh, KC Hsu, PH Liao, S Qiu… - Nature …, 2021 - nature.com
The limited availability of nasopharyngeal carcinoma-related progression biomarker array
kits that offer physicians comprehensive information is disadvantageous for monitoring …

Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients

F Klupp, L Neumann, C Kahlert, J Diers, N Halama… - BMC cancer, 2016 - Springer
Abstract Background Matrixmetalloproteinases (MMPs) comprise a family of zinc-dependent
endopeptidases which are involved in angiogenesis, tumor invasion and metastatic …

Energy transfer-based multiplexed assay of proteases by using gold nanoparticle and quantum dot conjugates on a surface

YP Kim, YH Oh, E Oh, S Ko, MK Han… - Analytical …, 2008 - ACS Publications
Rapid and sensitive assay of proteases and their inhibition in a high-throughput manner is of
great significance in the diagnostic and pharmaceutical fields. We developed a multiplexed …

Biomarkers for colorectal cancer

T Tanaka, M Tanaka, T Tanaka… - International journal of …, 2010 - mdpi.com
Colorectal cancer (CRC) is the third most common epithelial malignancy in the world. Since
CRC develops slowly from removable precancerous lesions, detection of the lesion at an …

Multiplex detection of pancreatic cancer biomarkers using a SERS-based immunoassay

N Banaei, A Foley, JM Houghton, Y Sun… - Nanotechnology, 2017 - iopscience.iop.org
Early diagnosis of pancreatic cancer (PC) is critical to reduce the mortality rate of this
disease. Current biological analysis approaches cannot robustly detect several low …

Noninvasive molecular biomarkers for the detection of colorectal cancer

HJ Kim, MH Yu, HG Kim, JH Byun, C Lee - BMB reports, 2008 - koreascience.kr
Colorectal cancer (CRC) is the third most common malignancy in the world. Because CRC
develops slowly from removable precancerous lesions, detection of the disease at an early …

Extracellular matrix biomarkers in colorectal cancer

MS Kim, SE Ha, M Wu, H Zogg, CF Ronkon… - International journal of …, 2021 - mdpi.com
The cellular microenvironment composition and changes therein play an extremely
important role in cancer development. Changes in the extracellular matrix (ECM), which …