Management of bleeding and coagulopathy following major trauma: an updated European guideline
Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient. When these recommendations are implemented patient …
of the bleeding trauma patient. When these recommendations are implemented patient …
Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature
PE Marik, HL Corwin - Critical care medicine, 2008 - journals.lww.com
Background: Red blood cell (RBC) transfusions are common in intensive care unit, trauma,
and surgical patients. However, the hematocrit that should be maintained in any particular …
and surgical patients. However, the hematocrit that should be maintained in any particular …
The European guideline on management of major bleeding and coagulopathy following trauma
DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …
around the world, and post-traumatic bleeding remains a leading cause of potentially …
The European guideline on management of major bleeding and coagulopathy following trauma
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …
Management of bleeding following major trauma: an updated European guideline
Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient, which when implemented may improve patient outcomes …
of the bleeding trauma patient, which when implemented may improve patient outcomes …
Clinical practice guideline: red blood cell transfusion in adult trauma and critical care
LM Napolitano, S Kurek, FA Luchette… - Critical care …, 2009 - journals.lww.com
Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …
trauma and critical care. Design: Meetings, teleconferences and electronic-based …
Complications of massive transfusion
KC Sihler, LM Napolitano - Chest, 2010 - Elsevier
Massive transfusion (MT) is a lifesaving treatment of hemorrhagic shock, but can be
associated with significant complications. The lethal triad of acidosis, hypothermia, and …
associated with significant complications. The lethal triad of acidosis, hypothermia, and …
Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage
Background: Traumatic coagulopathy contributes to early death by exsanguination and late
death in multiple organ failure. Recombinant Factor VIIa (rFVIIa, NovoSeven) is a …
death in multiple organ failure. Recombinant Factor VIIa (rFVIIa, NovoSeven) is a …
Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients
Background Transfusion has long been identified as a risk factor for acute lung injury
(ALI)/ARDS. No study has formally evaluated the transfusion of specific blood products as a …
(ALI)/ARDS. No study has formally evaluated the transfusion of specific blood products as a …
Red blood cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiply injury: a retrospective analysis from the Trauma …
Background To test whether an acute transfusion practice of packed red blood cells (pRBC):
fresh‐frozen plasma (FFP) 1: 1 would be associated with reduced mortality in acute bleeding …
fresh‐frozen plasma (FFP) 1: 1 would be associated with reduced mortality in acute bleeding …