The basolateral amygdala (BLA) is a cortical structure based on its cell types, connectivity
features, and developmental characteristics. This part of the amygdala is considered to be …

Amygdaloid circuits are involved in a variety of emotional and motivation-related behaviors
and are impacted by stress. The amygdala expresses several neuromodulatory systems …

Preclinical and clinical studies implicate endocannabinoids (eCBs) in fear extinction, but the
underlying neural circuit basis of these actions is unclear. Here, we employed in vivo …

Interneurons expressing cholecystokinin (CCK) and parvalbumin (PV) constitute two key
GABAergic controllers of hippocampal pyramidal cell output. Although the temporally …

Early life adversity (ELA) is associated with increased risk for stress-related disorders later in
life. The link between ELA and risk for psychopathology is well established but the …

GABAergic neurons are key circuit elements in cortical networks. Despite growing evidence
showing that inhibitory cells play a critical role in the lateral (LA) and basal (BA) amygdala …

Inhibitory interneurons are crucial to brain function and their dysfunction is implicated in
neuropsychiatric conditions. Emerging evidence indicates that cholecystokinin (CCK) …

Acetylcholine (ACh) is released from basal forebrain cholinergic neurons in response to
salient stimuli and engages brain states supporting attention and memory. These high ACh …

Posttraumatic stress disorder (PTSD) is a persistent, trauma induced psychiatric condition
characterized by lifelong complex cognitive, emotional and behavioral phenotype. Although …

Deficiencies in the ability to extinguish fear is a hallmark of Trauma-and stressor-related
disorders, Anxiety disorders, and certain other neuropsychiatric conditions. Hence, a greater …