The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

A significant body of work has investigated the effects of acute exercise, defined as a single
bout of physical activity, on mood and cognitive functions in humans. Several excellent …

In this monograph, we ask whether various kinds of intellectual, physical, and social
activities produce cognitive enrichment effects—that is, whether they improve cognitive …

Voluntary physical activity and exercise training can favorably influence brain plasticity by
facilitating neurogenerative, neuroadaptive, and neuroprotective processes. At least some of …

Before the 1990s it was widely believed that the adult brain was incapable of regenerating
neurons. However, it is now established that new neurons are continuously produced in the …

We provide a brief review of the literature on exercise effects on brain and cognition. To this
end, we focus on both prospective and retrospective human epidemiological studies that …

Research in humans and animals has shown that exercise improves mood and cognition.
Physical activity also causes a robust increase in neurogenesis in the dentate gyrus of the …

Mouse models have been indispensable for elucidating normal and pathological processes
that influence learning and memory. A widely used method for assessing these cognitive …

Advances in the management of pediatric brain tumors have increased survival rates in
children, but their quality of life is impaired due to cognitive deficits that arise from irradiation …

Mammals expend energy in many ways, including basic cellular maintenance and repair,
digestion, thermoregulation, locomotion, growth and reproduction. These processes can …