Hepatitis C virus (HCV) mainly replicates in the cytoplasm, where it easily establishes
persistent infection, resulting in chronic hepatitis, liver cirrhosis, and hepatocellular …

Hepatitis C virus (HCV) infection is a major cause of severe liver disease including chronic
hepatitis, cirrhosis and hepatocellular carcinoma. The HCV burden in public health is …

We report a new hepatitis C virus (HCV) genotype identified in patients originating from the
Democratic Republic of Congo. The prototype QC69 virus is shown to be a new lineage …

Plagues upon the Earth is a monumental history of humans and their germs. Weaving
together a grand narrative of global history with insights from cutting-edge genetics, Kyle …

Hepatitis C virus (HCV) genotype 4 is highly heterogeneous. HCV subtype 4r has been
suggested to be less responsive to direct‐acting antiviral (DAA) drug treatment than other …

Background Limited treatment data are available for hepatitis C virus (HCV) in sub-Saharan
Africa, especially for genotype 4. Our objective was to establish the safety and efficacy of …

Background & Aims HCV subtypes which are unusual in Europe are more prevalent in the
African region, but little is known of their response to direct-acting antivirals (DAAs). These …

The hepatitis C virus (HCV) is an extremely diverse virus, subtypes of which are distributed
variably around the world. Viral genotypes may be divided into epidemic subtypes; those …

Estimating viral timescales is fundamental in understanding the evolutionary biology of
viruses. Molecular clocks are widely used to reveal the recent evolutionary histories of …

The gut–liver-axis is a bidirectional coordination between the gut, including microbial
residents, the gut microbiota, from one side and the liver on the other side. Any disturbance …