Brain–machine interfaces (BMIs) create closed-loop control systems that interact with the
brain by recording and modulating neural activity and aim to restore lost function, most …

Cross-frequency coupling (CFC) reflects (nonlinear) interactions between signals of different
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …

Deep brain stimulation (DBS) has been successfully used to treat movement disorders, such
as Parkinson's disease, for more than 25 years and heralded the advent of electrical …

Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

Neural activity exhibits complex dynamics related to various brain functions, internal states
and behaviors. Understanding how neural dynamics explain specific measured behaviors …

Direct electrical stimulation can modulate the activity of brain networks for the treatment of
several neurological and neuropsychiatric disorders and for restoring lost function. However …

Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …

Continuous deep brain stimulation (cDBS) of the subthalamic nucleus (STN) or globus
pallidus is an effective treatment for the motor symptoms of Parkinson's disease. The relative …

Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …

Background Deep brain stimulation (DBS) is an effective therapy for reducing the motor
symptoms of Parkinson's disease, but the mechanisms of action of DBS and neural …