Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review

N Tavvabi-Kashani, M Hasanpour, VB Rahimi… - Toxicon, 2024 - Elsevier
The active biological phytochemicals, crucial compounds employed in creating hundreds of
medications, are derived from valuable and medicinally significant plants. These …

Histopathological effects, responses of oxidative stress, inflammation, apoptosis biomarkers and alteration of gene expressions related to apoptosis, oxidative stress …

S Altun, S Özdemir, H Arslan - Environmental Pollution, 2017 - Elsevier
In this study, we aimed to identify the toxic effects of chlorpyrifos exposure on the tissues of
common carp. For this purpose, we evaluated histopathological changes in the brain, gills …

Adverse effects of the pesticide chlorpyrifos on the physiology of a damselfly only occur at the cold and hot extremes of a temperature gradient

J Verheyen, K Cuypers, R Stoks - Environmental pollution, 2023 - Elsevier
Ecotoxicological studies considerably improved realism by assessing the toxicity of
pollutants at different temperatures. Nevertheless, they may miss key interaction patterns …

Effects of atrazine and chlorpyrifos on oxidative stress-induced autophagy in the immune organs of common carp (Cyprinus carpio L.)

D Chen, Z Zhang, H Yao, Y Liang, H **ng… - Fish & shellfish …, 2015 - Elsevier
Atrazine (ATR) and chlorpyrifos (CPF) are the most common agrochemical in the freshwater
ecosystems of the world. This study assessed the effects of ATR (4.28, 42.8 and 428 μg/L) …

Acute toxicity evaluation and immunomodulatory potential of hydrodynamic cavitation extract of citrus peels

DDP Putri, GG Maran, Y Kusumastuti… - Journal of Applied …, 2022 - japsonline.com
Citrus peels have been explored vastly due to their high methoxy flavonoid contents that
show several biological activities, including immunomodulation, anti-inflammation, and …

Neutrophil-lymphocyte ratio in patients with pesticide poisoning

ZD Dundar, M Ergin, R Koylu, R Ozer, B Cander… - The Journal of …, 2014 - Elsevier
Background Pesticides are highly toxic to human beings, and pesticide poisoning is
associated with high morbidity and mortality. The identification of powerful prognostic …

In vivo antioxidative and neuroprotective effect of 4-Allyl-2-methoxyphenol against chlorpyrifos-induced neurotoxicity in rat brain

V Singh, R Panwar - Molecular and cellular biochemistry, 2014 - Springer
Chlorpyrifos exposure leads to various neurological disorders adverting disturbance in
molecular pathways and normal brain functions. Major complications arise when these …

Effects of atrazine and chlorpyrifos on the production of nitric oxide and expression of inducible nitric oxide synthase in the brain of common carp (Cyprinus carpio L.)

LL Wang, T Liu, C Wang, FQ Zhao, ZW Zhang… - Ecotoxicology and …, 2013 - Elsevier
The study aimed to investigate the effects of atrazine (ATR), chlorpyrifos (CPF), and the
mixture of them on nitric oxide (NO) and inducible nitric oxide synthase (iNOS) in the brain of …

Effect of N-acetylcysteine on attenuation of chlropyrifos and its methyl analogue toxicity in male rats

KA Osman, EME El-Din, NS Ahmed, S Ayman - Toxicology, 2021 - Elsevier
The attenuating effect of 150 mg/kg of N-acetylcysteine (NAC) against the oral administration
of 7.88 and 202.07 mg/kg/day for 14 days of either chlropyrifos-ethyl (CPE-E) or chlropyrifos …

Molecular and biochemical evidences for beneficial effects of zinc oxide nanoparticles in modulation of chlorpyrifos toxicity in human lymphocytes

M Navaei-Nigjeh, M Gholami… - Iranian journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Chlorpyrifos (CP), an acetylcholinesterase (AChE) inhibitor, is used throughout the world as
an insecticide in agriculture and an eradicating agent for termites around homes. In the …