Mechanical properties and peculiarities of molecular crystals
In the last century, molecular crystals functioned predominantly as a means for determining
the molecular structures via X-ray diffraction, albeit as the century came to a close the …
the molecular structures via X-ray diffraction, albeit as the century came to a close the …
Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review
Wound healing can lead to complex clinical problems, hence finding an efficient approach to
enhance the healing process is necessary. An ideal wound dressing should treat wounds at …
enhance the healing process is necessary. An ideal wound dressing should treat wounds at …
[HTML][HTML] Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification
The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …
Terpenoids' anti-cancer effects: Focus on autophagy
Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …
[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …
has recently shown promising results. However, although these advances have been …
Application of ensemble machine learning approach to assess the factors affecting size and polydispersity index of liposomal nanoparticles
Liposome nanoparticles have emerged as promising drug delivery systems due to their
unique properties. Assessing particle size and polydispersity index (PDI) is critical for …
unique properties. Assessing particle size and polydispersity index (PDI) is critical for …
Drug solubility: importance and enhancement techniques
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system,
is one of the important parameters to achieve desired concentration of drug in systemic …
is one of the important parameters to achieve desired concentration of drug in systemic …
Strategies to address low drug solubility in discovery and development
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …
therefore, to variability in clinical response. Despite significant efforts to “design in” …
PLGA-based nanoparticles: an overview of biomedical applications
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …
biodegradable polymers. Among the different polymers developed to formulate polymeric …
[HTML][HTML] Overview of milling techniques for improving the solubility of poorly water-soluble drugs
ZH Loh, AK Samanta, PWS Heng - Asian journal of pharmaceutical …, 2015 - Elsevier
Milling involves the application of mechanical energy to physically break down coarse
particles to finer ones and is regarded as a “top–down” approach in the production of fine …
particles to finer ones and is regarded as a “top–down” approach in the production of fine …