Glycans linked to proteins and lipids and also occurring in free forms have many functions,
and these are partly elicited through specific interactions with glycan-binding proteins …

Immune checkpoints are crucial for regulating immune responses and maintaining self-
tolerance, as they play a pivotal role in preventing autoimmunity and facilitating tumor …

Breast cancer (BC) is the leading cause of death by cancer in women worldwide. Triple-
negative (TN) BC constitutes aggressive and highly metastatic tumors associated with …

A scalable, seven step synthesis is reported for a trifluoromethyl toluene protected
sulfonated phenylalanine building block whose utility was demonstrated in the synthesis of …

UDP-GalNAc polypeptide N-acetylgalactosaminyltransferases (GalNAc-Ts) catalyze mucin-
type O-glycosylation by transferring α-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to …

Breast cancer (BC) is the leading cause of death by cancer in women worldwide. Triple‑
negative (TN) BC constitutes aggressive and highly metastatic tumors associated with …

Chemokines are from a family of secreted cytokines that direct the trafficking of immune cells
to coordinate immune responses. Chemokines are involved in numerous disease states …

The emergence of glycomolecules in nature coincided with the dawning of the ribonucleic
acid (RNA) and deoxyribonucleic acid (DNA) world, along with the development of a …

Peptide O-glycosylation is a non-template-driven process that relies on the coordinated
action of glycosyltransferases (GTs) within the endoplasmic reticulum (ER) and Golgi …

Peptide O-glycosylation is a non-template driven process dependent on an orchestrated
collaboration of glycosyltransferases (GTs) in the ER and golgi apparatus. An in vitro …