Oxidative stress, inflammation, mitochondrial dysfunction, reduced protein synthesis, and
increased proteolysis are all critical factors in the process of muscle atrophy. In particular …

Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation,
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …

The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

Chronic kidney disease (CKD) is a high-risk chronic catabolic disease due to its high
morbidity and mortality. CKD is accompanied by many complications, leading to a poor …

Skeletal muscle diseases, a broad category encompassing a myriad of afflictions such as
acute muscle injury and muscular dystrophies, pose a significant health burden globally …

Aim: Diabetic sarcopenia leads to disability and seriously affects the quality of life. Currently,
there are no effective therapeutic strategies for diabetic sarcopenia. Our previous studies …

Skeletal muscle, the largest organ in the human body, plays a crucial role in supporting and
defending the body and is essential for movement. It also participates in regulating the …

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a multifaceted respiratory
disorder characterized by progressive airflow limitation and systemic implications. It has …

Denervated muscle atrophy is a common clinical disease that has no effective treatments.
Our previous studies have found that oxidative stress and inflammation play an important …

The molecular mechanism underlying denervation-induced muscle atrophy is complex and
incompletely understood. Our previous results suggested that inflammation may play an …