Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023‏ - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives

S Wang, Y Zheng, F Yang, L Zhu, XQ Zhu… - Signal transduction and …, 2021‏ - nature.com
Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …

Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation

K Wang, X Wang, Q Pan, B Zhao - Molecular cancer, 2023‏ - Springer
Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …

Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review

J Yang, R Xu, C Wang, J Qiu, B Ren… - Cancer …, 2021‏ - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …

A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021‏ - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Liquid biopsy in cancer current: status, challenges and future prospects

L Ma, H Guo, Y Zhao, Z Liu, C Wang, J Bu… - … and Targeted Therapy, 2024‏ - nature.com
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …

Circulating tumor cell isolation, culture, and downstream molecular analysis

S Sharma, R Zhuang, M Long, M Pavlovic, Y Kang… - Biotechnology …, 2018‏ - Elsevier
Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a
promising prognostic significance in cancer detection. Performing functional and molecular …

[HTML][HTML] Research progress of CTC, ctDNA, and EVs in cancer liquid biopsy

X Wang, L Wang, H Lin, Y Zhu, D Huang, M Lai… - Frontiers in …, 2024‏ - frontiersin.org
Circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vehicles
(EVs) have received significant attention in recent times as emerging biomarkers and …

Multibiomarker panels in liquid biopsy for early detection of pancreatic cancer–a comprehensive review

KL Reese, K Pantel, DJ Smit - Journal of Experimental & Clinical Cancer …, 2024‏ - Springer
Pancreatic ductal adenocarcinoma (PDAC) is frequently detected in late stages, which leads
to limited therapeutic options and a dismal overall survival rate. To date, no robust method …

Profile of the Roche cobas® EGFR mutation test v2 for non-small cell lung cancer

U Malapelle, R Sirera, E Jantus-Lewintre… - Expert review of …, 2017‏ - Taylor & Francis
Introduction: The discovery of driver mutations in non-small cell lung cancer (NSCLC) has
led to the development of genome-based personalized medicine. Fifteen to 20% of …