Human amniotic epithelial cells (hAECs) derived from placental tissues have gained
considerable attention in the field of regenerative medicine. hAECs possess embryonic stem …

One of the main aims in regenerative medicine is to find stem cells that are easy to obtain
and are safe and efficient in either an autologous or allogenic host when transplanted. This …

In 2010, we published a review summarizing the role of the transforming growth factor-beta
(TGFβ) family of proteins in diabetes. At that time there were still many outstanding questions …

Efficiency of the induction protocol is crucial for the generation of insulin-producing cells
(IPCs) from human dental pulp stem cells (hDPSCs). Here, we established the integrative …

As of 2000, the success of pancreatic islet transplantation using the Edmonton protocol to
treat type I diabetes mellitus still faced some obstacles. These include the limited number of …

Both type 1 and type 2 diabetes are conditions that are associated with the loss of insulin-
producing β-cells within the pancreas. An active research therefore aims at regenerating …

Background Despite the recent progress in the differentiation strategies of stem cells into
pancreatic beta cell lineage, current protocols are not optimized for different cell types. The …

Objectives Embryonic stem cells (ESCs)–derived pancreatic precursor cells have great
potential for pancreas repair. Expression of pancreatic duodenal homeobox 1 (Pdx1) in …

Human amniotic epithelial cells (hAECs) derived from placental tissues have gained
considerable attention in the field of regenerative medicine. hAECs possess embryonic stem …

Background The specific precursor cells derived from embryonic stem cells (ESCs) after
induced differentiation offers great potential for repairing damaged pancreas. Therefore, it is …