The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …

There has been a resurgence in gene therapy efforts that is partly fueled by the identification
and understanding of new gene delivery vectors. Adeno-associated virus (AAV) is a non …

Biopharmaceuticals have emerged to play a vital role in disease treatment and have shown
promise in the rapidly expanding pharmaceutical market due to their high specificity and …

Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …

Nuclear targeting of therapeutics provides a strategy for enhancing efficacy of molecules
active in the nucleus and minimizing off-target effects.'Active'nuclear-directed transport and …

Protein therapy exhibits several advantages over small molecule drugs and is increasingly
being developed for the treatment of disorders ranging from single enzyme deficiencies to …

Global cancer prevalence has continuously increased in the last decades despite
substantial progress achieved for patient care. Cancer is no longer recognized as a singular …

In the late 70's, the discovery of the restriction enzymes made possible the biological
production of functional proteins by recombinant DNA technologies, a fact that largely …

Metal-organic frameworks (MOFs) have emerged as a class of versatile materials, finding
extensive applications in drug delivery because of their unique properties and flexible …

The use of drug delivery vehicles to improve the efficacy of drugs and to target their action at
effective concentrations over desired periods of time has been an active topic of research …