Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …

Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …

Background Immune thrombocytopenia (ITP) is an autoimmune disease characterized by
autoantibody-mediated platelet destruction. Treatment with CM313, a novel anti-CD38 …

Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

Immune thrombocytopenia (ITP) is traditionally considered an antibody-mediated disease.
However, a number of features suggest alternative mechanisms of platelet destruction. In …

Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder mediated by
antiplatelet autoantibodies and antigen-specific T cells that either destroy platelets …

Immune thrombocytopenia (ITP) is a rare autoimmune disease due to both a peripheral
destruction of platelets and an inappropriate bone marrow production. Although the primary …

Immune thrombocytopenia (ITP) is an autoantibody-mediated bleeding disorder with both
accelerated platelet destruction and impaired platelet production. We and others have …

Over the past decades, a wealth of information has been reported about the pathogenic
features of immune thrombocytopenia (ITP). To this day, however, it is unclear whether the …