Despite being the hallmark of cancer that is responsible for the highest number of deaths,
very little is known about the biology of metastasis. Metastatic disease typically manifests …

Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Metastatic dissemination occurs very early in the malignant progression of a cancer but the
clinical manifestation of metastases often takes years. In recent decades, 5-year survival of …

Liquid biopsy has been introduced as a new diagnostic concept predicated on the analysis
of circulating tumour cells (CTCs) or circulating tumour-derived factors, in particular, cell-free …

Current clinical tools for breast cancer (BC) diagnosis are insufficient but liquid biopsy of
different bodily fluids has recently emerged as a minimally invasive strategy that provides a …

Background Extended, more effective breast cancer treatments have increased the
prevalence of long-term survivors. We investigated the risk of late breast cancer recurrence …

The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an
important role in both development and cancer progression. Depending on the contextual …

Abstract “Liquid biopsy” focusing on the analysis of circulating tumor cells (CTC) and
circulating cell-free tumor DNA (ctDNA) in the blood of patients with cancer has received …

Exosomes play an important role in intercellular communication and metastatic progression
of hepatocellular carcinoma (HCC). However, cellular communication between …