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APT‐weighted MRI: techniques, current neuro applications, and challenging issues
J Zhou, HY Heo, L Knutsson… - Journal of Magnetic …, 2019 - Wiley Online Library
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …
generates image contrast based predominantly on the amide protons in mobile cellular …
Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum
PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …
Clinical applications of chemical exchange saturation transfer (CEST) MRI
KM Jones, AC Pollard, MD Pagel - Journal of Magnetic …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
been developed and employed in multiple clinical imaging research centers worldwide …
been developed and employed in multiple clinical imaging research centers worldwide …
Chemical exchange saturation transfer (CEST): what is in a name and what isn't?
PCM Van Zijl, NN Yadav - Magnetic resonance in medicine, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is a relatively new magnetic
resonance imaging contrast approach in which exogenous or endogenous compounds …
resonance imaging contrast approach in which exogenous or endogenous compounds …
Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades
O Togao, T Yoshiura, J Keupp, A Hiwatashi… - Neuro …, 2014 - academic.oup.com
Background Amide proton transfer (APT) imaging is a novel molecular MRI technique to
detect endogenous mobile proteins and peptides through chemical exchange saturation …
detect endogenous mobile proteins and peptides through chemical exchange saturation …
Tumor pH and its measurement
X Zhang, Y Lin, RJ Gillies - Journal of Nuclear Medicine, 2010 - jnm.snmjournals.org
Studies over the last few decades have demonstrated that the intracellular pH of solid
tumors is maintained within a range of 7.0–7.2, whereas the extracellular pH is acidic. A low …
tumors is maintained within a range of 7.0–7.2, whereas the extracellular pH is acidic. A low …
Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides
J Zhou, E Tryggestad, Z Wen, B Lal, T Zhou… - Nature medicine, 2011 - nature.com
It remains difficult to distinguish tumor recurrence from radiation necrosis after brain tumor
therapy. Here we show that these lesions can be distinguished using the amide proton …
therapy. Here we show that these lesions can be distinguished using the amide proton …
Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7 T
Chemical exchange saturation transfer (CEST) is a magnetization transfer (MT) technique to
indirectly detect pools of exchangeable protons through the water signal. CEST MRI has …
indirectly detect pools of exchangeable protons through the water signal. CEST MRI has …
Natural D‐glucose as a biodegradable MRI contrast agent for detecting cancer
KWY Chan, MT McMahon, Y Kato, G Liu… - Magnetic resonance …, 2012 - Wiley Online Library
Purpose: Modern imaging technologies such as CT, PET, SPECT, and MRI employ contrast
agents to visualize the tumor microenvironment, providing information on malignancy and …
agents to visualize the tumor microenvironment, providing information on malignancy and …
CEST: from basic principles to applications, challenges and opportunities
E Vinogradov, AD Sherry, RE Lenkinski - Journal of magnetic resonance, 2013 - Elsevier
Chemical Exchange Saturation Transfer (CEST) offers a new type of contrast for MRI that is
molecule specific. In this approach, a slowly exchanging NMR active nucleus, typically a …
molecule specific. In this approach, a slowly exchanging NMR active nucleus, typically a …