Branched chain amino acids, aging and age-related health

DG Le Couteur, SM Solon-Biet, VC Cogger… - Ageing research …, 2020 - Elsevier
Branched chain amino acids (BCAA: leucine, valine, isoleucine) have key physiological
roles in the regulation of protein synthesis, metabolism, food intake and aging. Many studies …

Branched-chain amino acids in metabolic signalling and insulin resistance

CJ Lynch, SH Adams - Nature Reviews Endocrinology, 2014 - nature.com
Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and
indirect effects. Frequently, BCAAs have been reported to mediate antiobesity effects …

Microbially produced imidazole propionate impairs insulin signaling through mTORC1

A Koh, A Molinaro, M Ståhlman, MT Khan, C Schmidt… - Cell, 2018 - cell.com
Interactions between the gut microbiota, diet, and the host potentially contribute to the
development of metabolic diseases. Here, we identify imidazole propionate as a microbially …

[HTML][HTML] Impacts of essential amino acids on energy balance

F ** diabetes, metabolic syndrome, dyslipidemia and hypertension in Japanese population
M Yamakado, K Nagao, A Imaizumi, M Tani, A Toda… - Scientific reports, 2015 - nature.com
Plasma free amino acid (PFAA) profile is highlighted in its association with visceral obesity
and hyperinsulinemia and future diabetes. Indeed PFAA profiling potentially can evaluate …

[HTML][HTML] Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective

A Valerio, G D'Antona, E Nisoli - Aging (albany NY), 2011 - ncbi.nlm.nih.gov
Malnutrition is common among older persons, with important consequences increasing
frailty and morbidity and reducing health expectancy. On the contrary, calorie restriction (CR …

Metabolic and physiological roles of branched‐chain amino acids

MD Monirujjaman, A Ferdouse - Advances in Molecular Biology, 2014 - Wiley Online Library
Branch chain amino acids (BCAAs) have unique properties with diverse physiological and
metabolic roles. They have functions other than simple nutrition. Different diseases including …

Hibiscus sabdariffa extract inhibits obesity and fat accumulation, and improves liver steatosis in humans

HC Chang, CH Peng, DM Yeh, ES Kao, CJ Wang - Food & function, 2014 - pubs.rsc.org
Obesity is associated with a great diversity of diseases including non-alcoholic fatty liver
disease. Our previous report suggested that Hibiscus sabdariffa extracts (HSE) had a …