Molecular biomarkers for vascular cognitive impairment and dementia

S Hosoki, GK Hansra, T Jayasena, A Poljak… - Nature Reviews …, 2023 - nature.com
As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

Arteriolar neuropathology in cerebral microvascular disease

C Fang, SD Magaki, RC Kim, RN Kalaria… - Neuropathology and …, 2023 - Wiley Online Library
Cerebral microvascular disease (MVD) is an important cause of vascular cognitive
impairment. MVD is heterogeneous in aetiology, ranging from universal ageing to the …

The Spectrum of Cerebral Small Vessel Disease: emerging pathophysiologic constructs and management strategies

RT Muir, EE Smith - Neurologic Clinics, 2024 - neurologic.theclinics.com
Cerebral small vessel disease (CSVD) results in a spectrum of neurologic, behavioral, and
cognitive sequelae, most commonly from white matter hyperintensities (WMH) of presumed …

Incidence of microvascular dysfunction is increased in hyperlipidemic mice, reducing cerebral blood flow and impairing remote memory

LD Hernandez Torres, F Rezende, E Peschke… - Frontiers in …, 2024 - frontiersin.org
Introduction The development of cognitive dysfunction is not necessarily associated with diet-
induced obesity. We hypothesized that cognitive dysfunction might require additional …

Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage

K Nakagawa, R Chen, SM Greenberg… - Journal of …, 2022 - journals.lww.com
Objective: Since the G allele of forkhead box O3 (FOXO3) single nucleotide polymorphism
(SNP) rs2802292 is associated with resilience and longevity, ostensibly by mitigating the …

In vivo visualisation of Charcot-Bouchard Aneurysms on lenticulostriate arteries using 7T MRI

Y Jiaerken, P Benjamin, CT Rodgers, L Cai… - American Journal of …, 2025 - ajnr.org
ABSTRACT BACKGROUND AND PURPOSE: Charcot-Bouchard Aneurysms (CBA) are tiny
aneurysms arising from small perforating arteries. Despite the potentially catastrophic …

Intracranial aneurysms and subarachnoid hemorrhage

MR Harrigan, JP Deveikis - Handbook of Cerebrovascular Disease and …, 2024 - Springer
An aneurysm is an abnormal dilatation of an artery. In layman terms, an aneurysm can be
thought of as a weak spot in the wall of an artery, similar to a garden hose that has been filed …

Charcot Bouchard aneurysm: Case report and critical literature review

L Canbeldek, WI Rosenblum - Journal of Neuropathology & …, 2024 - academic.oup.com
To the Editor: In 1868 Charcot and Bouchard described “miliary aneurysms” arising from
arterioles usually less than 300 microns in diameter. They postulated that, when ruptured …

Characterizing Plasma Biomarkers of Cerebral Amyloid Angiopathy

RT Muir - 2024 - prism.ucalgary.ca
BACKGROUND: Cerebral Amyloid Angiopathy (CAA) is characterized by the progressive
deposition of beta-amyloid in cortical and leptomeningeal small vessels leading to …

Determinación de variables pronósticas de mortalidad y recuperación funcional en hemorragia intracerebral espontánea

A Ramos Pachon - 2023 - ddd.uab.cat
Introducció i objectiu: L'hemorràgia intracerebral espontània (HIC) és un subtipus d'ictus
associat amb alta mortalitat, morbiditat i impacte econòmic. Actualment, no hi ha tractaments …