ABSTRACT A long-standing goal of spinal cord injury research is to develop effective spinal
cord repair strategies for the clinic. Rat models of spinal cord injury provide an important …

Spinal cord injury (SCI) is an as yet untreatable neuropathology that causes severe
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …

Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

A phase 1 open-label, non-randomized clinical trial was conducted to determine feasibility
and safety of autologous human Schwann cell (ahSC) transplantation accompanied by …

Facilitating axon regeneration in the injured central nervous system remains a challenging
task. RAF-MAP2K signaling plays a key role in axon elongation during nervous system …

Spinal cord injury (SCI) leads to numerous chronic and debilitating functional deficits that
greatly affect quality of life. While many pharmacological interventions have been explored …

Spinal cord injury (SCI), resulting in para-and tetraplegia caused by the partial or complete
disruption of descending motor and ascending sensory neurons, represents a complex …

Neurorehabilitation is a newer and smaller subspecialty in neurology and is largely
dominated by neurologists concerned with stroke and brain injury. Spinal cord injury and …

Spinal cord injury is a devastating condition that is followed by long and often unsuccessful
recovery after trauma. The state of the art approach to manage paralysis and concomitant …

Spinal cord injury (SCI) is a devastating condition that affects approximately 294,000 people
in the USA and several millions worldwide. The corticospinal motor circuitry plays a major …