The bone extracellular matrix in bone formation and regeneration

X Lin, S Patil, YG Gao, A Qian - Frontiers in pharmacology, 2020 - frontiersin.org
Bone regeneration repairs bone tissue lost due to trauma, fractures, and tumors, or absent
due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio …

Vitamin K–sources, physiological role, kinetics, deficiency, detection, therapeutic use, and toxicity

P Mladěnka, K Macáková, L Kujovská Krčmová… - Nutrition …, 2022 - academic.oup.com
Vitamin K is traditionally connected with blood coagulation, since it is needed for the
posttranslational modification of 7 proteins involved in this cascade. However, it is also …

The osteocyte: new insights

AG Robling, LF Bonewald - Annual review of physiology, 2020 - annualreviews.org
Osteocytes are an ancient cell, appearing in fossilized skeletal remains of early fish and
dinosaurs. Despite its relative high abundance, even in the context of nonskeletal cells, the …

Paracrine and endocrine actions of bone—the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts

Y Han, X You, W **ng, Z Zhang, W Zou - Bone research, 2018 - nature.com
The skeleton is a dynamic organ that is constantly remodeled. Proteins secreted from bone
cells, namely osteoblasts, osteocytes, and osteoclasts exert regulation on …

Bone physiology as inspiration for tissue regenerative therapies

D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

ZIF-8-modified multifunctional bone-adhesive hydrogels promoting angiogenesis and osteogenesis for bone regeneration

Y Liu, Z Zhu, X Pei, X Zhang, X Cheng… - … Applied Materials & …, 2020 - ACS Publications
Designing bone adhesives with adhesiveness, antideformation, biocompatibility, and
biofunctional effects has great practical significance for bone defect reconstructive treatment …

[HTML][HTML] Nutritional supplements and complementary therapies in polycystic ovary syndrome

S Alesi, C Ee, LJ Moran, V Rao, A Mousa - Advances in Nutrition, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) affects 1 in 5 women of reproductive age, and is
characterized by menstrual irregularities, clinical or biochemical hyperandrogenism, and the …

Bioprinting macroporous hydrogel with aqueous two‐phase emulsion‐based bioink: in vitro mineralization and differentiation empowered by phosphorylated cellulose …

Q Wang, Ö Karadas, JM Rosenholm… - Advanced Functional …, 2024 - Wiley Online Library
Aqueous two‐phase emulsion (ATPE)‐based bioinks, a creative innovation for bioprinting,
enable the fabrication of complex 3D cell‐laden hydrogels with macroporous structure …

Bone marrow mesenchymal stem cells-derived exosomal MiR-29b-3p regulates aging-associated insulin resistance

T Su, Y **ao, YE **ao, QI Guo, C Li, Y Huang, Q Deng… - ACS …, 2019 - ACS Publications
Insulin resistance is the major pathological characteristic of type 2 diabetes, and the elderly
often develop insulin resistance. However, the deep-seated mechanisms for aging-related …

Hormonal regulation of biomineralization

A Arnold, E Dennison, CS Kovacs… - Nature Reviews …, 2021 - nature.com
Biomineralization is the process by which organisms produce mineralized tissues. This
crucial process makes possible the rigidity and flexibility that the skeleton needs for …