Melatonergic receptors (Mt1/Mt2) as a potential additional target of novel drugs for depression

DI Boiko, AD Shkodina, MM Hasan, M Bardhan… - Neurochemical …, 2022 - Springer
A complex pathogenesis involving several physiological systems is theorized to underline
the development of depressive disorders. Depression is accompanied by circadian …

NADPH and mitochondrial quality control as targets for a circadian-based fasting and exercise therapy for the treatment of Parkinson's disease

WM Curtis, WA Seeds, MP Mattson, PC Bradshaw - Cells, 2022 - mdpi.com
Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …

Neuroprotective effect of melatonin on Sleep disorders Associated with Parkinson's Disease

X Hu, J Li, X Wang, H Liu, T Wang, Z Lin, N **ong - Antioxidants, 2023 - mdpi.com
Parkinson's disease (PD) is a complex, multisystem disorder with both neurologic and
systemic manifestations, which is usually associated with non-motor symptoms, including …

Sleep and sleep disorders in people with Parkinson's disease

A Iranzo, VC De Cock, ML Fantini… - The Lancet …, 2024 - thelancet.com
Sleep disorders are common in people with Parkinson's disease. These disorders, which
increase in frequency throughout the course of the neurodegenerative disease and impair …

Cognitive impairment in multiple sclerosis

K Maiese - Bioengineering, 2023 - mdpi.com
Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five …

Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view

P Raee, SC Tan, S Najafi, F Zandsalimi, TY Low… - Reproductive Biology …, 2023 - Springer
Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in
the degradation and recycling of cellular components. There is growing evidence that …

Is obstructive sleep apnea a circadian rhythm disorder?

J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …

Mental health and sleep disturbances among Ukrainian refugees in the context of Russian-Ukrainian war: A preliminary result from online-survey

DI Boiko, PO Shyrai, OV Mats, ZI Karpik, MH Rahman… - Sleep Medicine, 2024 - Elsevier
Abstract The ongoing Russian-Ukrainian conflict has caused a significant displacement of
individuals, with an estimated five million Ukrainians seeking temporary refuge in other …

[HTML][HTML] Schizophrenia and disruption of circadian rhythms: An overview of genetic, metabolic and clinical signs

DI Boiko, H Chopra, M Bilal, PV Kydon… - Schizophrenia …, 2024 - Elsevier
A molecular clock in the suprachiasmatic nucleus of the anterior hypothalamus, which is
entrained by the dark-light cycle and controls the sleep-wake cycle, regulates circadian …

Dietary supplementation with resveratrol attenuates serum melatonin level, pro-inflammatory response and metabolic disorder in rats fed high-fructose high-lipid diet …

Y Frenkel, V Cherno, H Kostenko, H Chopra… - Pathophysiology, 2023 - mdpi.com
This study aims to investigate the effect of resveratrol on systemic inflammatory response
and metabolic disorder in rats fed a high-fructose high-lipid diet (HFHLD) and exposed to …