Cancer is the leading cause of death worldwide, and its treatment and outcomes have been
dramatically revolutionised by targeted therapies. As the most frequently mutated oncogene …

The RAS family of oncogenes (HRAS, NRAS, and KRAS) are among the most frequently
mutated protein families in cancers. RAS-mutated tumors were originally thought to …

The pancreas represents an important organ that has not been comprehensively studied in
many fields. To fill this gap, many models have been generated, and traditional models have …

Simple Summary BRAF is a protein kinase that is frequently mutationally activated in cancer.
Mutant BRAF can be pharmacologically inhibited, which in combination with blockade of its …

Simple Summary Cancer is caused by changes in DNA called mutations that alter the way
proteins work. We know that RAS proteins are one of the most commonly mutated proteins in …

Cancer research in Rwanda is estimated to be less than 1% of the total African cancer
research output with limited research on colorectal cancer (CRC). Rwandan patients with …