The wound microbiota: microbial mechanisms of impaired wound healing and infection

A Uberoi, A McCready-Vangi, EA Grice - Nature Reviews Microbiology, 2024 - nature.com
The skin barrier protects the human body from invasion by exogenous and pathogenic
microorganisms. A breach in this barrier exposes the underlying tissue to microbial …

Biofilms: Formation, drug resistance and alternatives to conventional approaches

R Mirghani, T Saba, H Khaliq, J Mitchell… - AIMS …, 2022 - pmc.ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Biofilm dispersion

KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

Biofilms: hot spots of horizontal gene transfer (HGT) in aquatic environments, with a focus on a new HGT mechanism

K Abe, N Nomura, S Suzuki - FEMS microbiology ecology, 2020 - academic.oup.com
Biofilms in water environments are thought to be hot spots for horizontal gene transfer (HGT)
of antibiotic resistance genes (ARGs). ARGs can be spread via HGT, though mechanisms …

Interrogating the viral dark matter of the rumen ecosystem with a global virome database

M Yan, AA Pratama, S Somasundaram, Z Li… - Nature …, 2023 - nature.com
The diverse rumen virome can modulate the rumen microbiome, but it remains largely
unexplored. Here, we mine 975 published rumen metagenomes for viral sequences, create …

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

The evolution and ecology of bacterial warfare

ET Granato, TA Meiller-Legrand, KR Foster - Current biology, 2019 - cell.com
Bacteria have evolved a wide range of mechanisms to harm and kill their competitors,
including chemical, mechanical and biological weapons. Here we review the incredible …

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

JM Sweere, JD Van Belleghem, H Ishak, MS Bach… - Science, 2019 - science.org
INTRODUCTION We have identified previously unsuspected, directly pathogenic roles for
bacteriophage (phage) virions in bacterial infections. In particular, we report that …

The DNA damage inducible SOS response is a key player in the generation of bacterial persister cells and population wide tolerance

Z Podlesek, D Žgur Bertok - Frontiers in microbiology, 2020 - frontiersin.org
Population-wide tolerance and persisters enable susceptible bacterial cells to endure
hostile environments, including antimicrobial exposure. The SOS response can play a …

[HTML][HTML] Mechanisms of antibiotic resistance in Pseudomonas aeruginosa biofilms

M Fernández-Billón, AE Llambías-Cabot… - Biofilm, 2023 - Elsevier
Pseudomonas aeruginosa is a major cause of life-threatening acute infections and life-long
lasting chronic infections. The characteristic biofilm mode of life in P. aeruginosa chronic …