Functional genomics data: privacy risk assessment and technological mitigation

G Gürsoy, T Li, S Liu, E Ni, CM Brannon… - Nature Reviews …, 2022 - nature.com
The generation of functional genomics data by next-generation sequencing has increased
greatly in the past decade. Broad sharing of these data is essential for research …

Legal aspects of privacy-enhancing technologies in genome-wide association studies and their impact on performance and feasibility

A Brauneck, L Schmalhorst, S Weiss, L Baumbach… - Genome Biology, 2024 - Springer
Genomic data holds huge potential for medical progress but requires strict safety measures
due to its sensitive nature to comply with data protection laws. This conflict is especially …

SoK: Fully homomorphic encryption compilers

A Viand, P Jattke, A Hithnawi - 2021 IEEE Symposium on …, 2021 - ieeexplore.ieee.org
Fully Homomorphic Encryption (FHE) allows a third party to perform arbitrary computations
on encrypted data, learning neither the inputs nor the computation results. Hence, it provides …

Efficient bootstrap** for approximate homomorphic encryption with non-sparse keys

JP Bossuat, C Mouchet, J Troncoso-Pastoriza… - … Conference on the …, 2021 - Springer
We present a bootstrap** procedure for the full-RNS variant of the approximate
homomorphic-encryption scheme of Cheon et al., CKKS (Asiacrypt 17, SAC 18). Compared …

The evolving privacy and security concerns for genomic data analysis and sharing as observed from the iDASH competition

TT Kuo, X Jiang, H Tang, XF Wang… - Journal of the …, 2022 - academic.oup.com
Concerns regarding inappropriate leakage of sensitive personal information as well as
unauthorized data use are increasing with the growth of genomic data repositories …

Memfhe: End-to-end computing with fully homomorphic encryption in memory

S Gupta, R Cammarota, T Šimunić - ACM Transactions on Embedded …, 2024 - dl.acm.org
The increasing amount of data and the growing complexity of problems have resulted in an
ever-growing reliance on cloud computing. However, many applications, most notably in …

Secure tumor classification by shallow neural network using homomorphic encryption

S Hong, JH Park, W Cho, H Choe, JH Cheon - BMC genomics, 2022 - Springer
Background Disclosure of patients' genetic information in the process of applying machine
learning techniques for tumor classification hinders the privacy of personal information …

Privacy-enhancing technologies in biomedical data science

H Cho, D Froelicher, N Dokmai, A Nandi… - Annual review of …, 2024 - annualreviews.org
The rapidly growing scale and variety of biomedical data repositories raise important privacy
concerns. Conventional frameworks for collecting and sharing human subject data offer …

Sine series approximation of the mod function for bootstrap** of approximate HE

CS Jutla, N Manohar - Annual International Conference on the Theory and …, 2022 - Springer
While it is well known that the sawtooth function has a point-wise convergent Fourier series,
the rate of convergence is not the best possible for the application of approximating the mod …

TrustGWAS: A full-process workflow for encrypted GWAS using multi-key homomorphic encryption and pseudorandom number perturbation

M Yang, C Zhang, X Wang, X Liu, S Li, J Huang… - Cell Systems, 2022 - cell.com
The statistical power of genome-wide association studies (GWASs) is affected by the
effective sample size. However, the privacy and security concerns associated with individual …