Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Osteoarthritis (OA) is a degenerative joint disease and is the main cause of chronic pain and
functional disability in adults. Articular cartilage is a hydrated soft tissue that is composed of …

Rheumatoid arthritis (RA) remains a formidable healthcare challenge due to its chronic
nature and potential for irreversible joint damage. Methotrexate (MTX) is a cornerstone …

Regenerative medicine is a highly regarded multidisciplinary field that aims to transform the
future of clinical medicine through curative strategies rather than palliative therapies. As an …

Hyaluronic acid (HA), a biodegradable, biocompatible and non-immunogenic therapeutic
polymer is a key component of the cartilage extracellular matrix (ECM) and has been widely …

The application of collagen‐based hydrogel is severely restricted due to its poor mechanical
strength and functional singleness. In this paper, two‐dimensional MXene nanosheets were …

Rheumatoid arthritis (RA) is a chronic inflammatory condition triggered by abnormal
autoimmune responses. Key characteristics of RA include the deterioration of joints and …

Treatment of osteoarthritis (OA) remains a significant clinical challenge. Itaconate (IA), an
emerging regulator of intracellular inflammation and oxidative stress, may potentially be …

Hydrogels are insoluble three-dimensional polymer networks that are water insoluble but
can absorb large amounts of water or biological fluid. They can be prepared using a variety …

The intra-articular administration of drugs has attracted great interest in recent decades for
the treatment of osteoarthritis. The use of modified drugs has also attracted interest in recent …