[HTML][HTML] Carnosine Supplementation Has No Effect on Inflammatory Markers in Adults with Prediabetes and Type 2 Diabetes: A Randomised Controlled Trial

S Saadati, M de Courten, C Deceneux, M Plebanski… - Nutrients, 2024 - mdpi.com
Background/Objectives: In vitro studies suggest that carnosine reduces inflammation by
upregulating anti-inflammatory mediators and downregulating pro-inflammatory cytokines …

The impact of carnosine on biological ageing–A geroscience approach

Q Wang, S Sadati, RH Kabthymer, LK Gadanec… - Maturitas, 2024 - Elsevier
Biological ageing involves a gradual decline in physiological function and resilience,
marked by molecular, cellular, and systemic changes across organ systems. Geroscience …

Electrophoretic determination of L-carnosine in health supplements using an integrated lab-on-a-chip platform with contactless conductivity detection

I Pukleš, C Páger, N Sakač, B Šarkanj… - International journal of …, 2023 - mdpi.com
The health supplement industry is one of the fastest growing industries in the world, but
there is a lack of suitable analytical methods for the determination of active compounds in …

Comparative evaluation of different modalities for measuring in vivo carnosine levels

AR Amraotkar, D Hoetker, MJ Negahdar, CK Ng… - Plos one, 2024 - journals.plos.org
Carnosine is an endogenous di-peptide (β-alanine-L-histidine) involved in maintaining
tissue homeostasis. It is most abundant in skeletal muscle where its concentration has been …

[HTML][HTML] The Effect of Carnosine Supplementation on Musculoskeletal Health in Adults with Prediabetes and Type 2 Diabetes: A Secondary Analysis of a Randomized …

S Saadati, P Jansons, D Scott, M de Courten, A Mousa… - Nutrients, 2024 - mdpi.com
Background/Objectives: Type 2 diabetes (T2D) is associated with an increased risk of
adverse musculoskeletal outcomes likely due to heightened chronic inflammation, oxidative …

Iron scavenging and suppression of collagen cross-linking underlie antifibrotic effects of carnosine in the heart with obesity

IA Berdaweel, TB Monroe, AA Alowaisi… - Frontiers in …, 2024 - frontiersin.org
Oral consumption of histidyl dipeptides such as l-carnosine has been suggested to promote
cardiometabolic health, although therapeutic mechanisms remain incompletely understood …

Evaluation of supplementary carnosine accumulation and distribution: an initial analysis of participants in the Nucleophilic Defense Against PM Toxicity (NEAT) clinical …

SP Baba, AR Amraotkar, D Hoetker, H Gao, D Gomes… - Amino Acids, 2024 - Springer
Carnosine is an endogenous dipeptide that buffers intracellular pH and quenches toxic
products of lipid peroxidation. Used as a dietary supplement, it also supports exercise …

[HTML][HTML] Assessing carnosinase 1 activity for diagnosing congenital disorders of glycosylation

L Interdonato, N Himmelreich, SF Garbade… - Molecular Genetics and …, 2024 - Elsevier
Abstract Diagnosing Congenital Disorders of Glycosylation (CDG) is challenging due to
clinical heterogeneity and the limited sensitivity of the classic serum transferrin isoelectric …

β‐alanine supplementation in adults with overweight and obesity: a randomized controlled feasibility trial

JJ Matthews, JV Creighton, J Donaldson, PA Swinton… - …, 2025 - Wiley Online Library
Objective Overweight and obesity are characterized by excess adiposity and systemic,
chronic, low‐grade inflammation, which is associated with several metabolic disorders. The …

[PDF][PDF] THE EFFECTS OF ANTIOXIDANT SUPPLEMENTS IN THE DIABETES TYPE 2 PATIENTS MANAGEMENT-A SYSTEMATIC

DA FĂRCAȘ - amtsibiu.ro
The pathology of Diabetes is closely related to oxidative stress and its reactive oxygen
species (ROS). Hyperglycemia causes ROS, and these, in turn, cause micro and …