The global risk of viral disease outbreaks emphasizes the need for rapid, accurate, and
sensitive detection techniques to speed up diagnostics allowing early intervention. An …

Mpox is a zoonotic disease caused by monkeypox virus (MPXV) from the Orthopoxvirus
genus. Unprecedented transmission events have led to more than 70 000 cases reported …

Super-resolution microscopy depends on steps that can contribute to the formation of image
artifacts, leading to misinterpretation of biological information. We present NanoJ …

Coronavirus particles are enveloped and pleomorphic and are thus refractory to
crystallization and symmetry-assisted reconstruction. A novel methodology of single-particle …

Cells secrete various membrane-enclosed microvesicles from their cell surface (shedding
microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly …

Influenza virus remains a global health threat, with millions of infections annually and the
impending threat that a strain of avian influenza may develop into a human pandemic …

▪ Abstract Electron tomography (ET) is uniquely suited to obtain three-dimensional
reconstructions of pleomorphic structures, such as cells, organelles or supramolecular …

Viruses infecting cells from the three domains of life, Archaea, Bacteria and Eukarya, share
homologous features, suggesting that viruses originated very early in the evolution of life …

For many viruses, one or two proteins enable cell binding, membrane fusion and entry. The
large number of proteins employed by poxviruses is unprecedented and may be related to …

Poxviruses comprise a large family of viruses characterized by a large, linear dsDNA
genome, a cytoplasmic site of replication and a complex virion morphology. The most …