Heterocycles: versatile control elements in bioactive macrocycles
HS Soor, SD Appavoo, AK Yudin - Bioorganic & Medicinal Chemistry, 2018 - Elsevier
The potential of macrocyclic peptides as therapeutics has garnered much attention over the
last several years. Unlike their linear counterparts, macrocycles have higher resistance to …
last several years. Unlike their linear counterparts, macrocycles have higher resistance to …
Synthesis, spectroscopic characterization, second and third-order nonlinear optical properties, and DFT calculations of a novel Mn (II) complex
A novel Mn (II) complex with 1, 3-Thiazolidine-2, 4-dicarboxylic acid and 1, 10
phenanthroline has been synthesized, and its FT-IR, FT-Raman and UV–vis spectra have …
phenanthroline has been synthesized, and its FT-IR, FT-Raman and UV–vis spectra have …
Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands
Herein we report on the synthesis and DNA binding properties of a new class of water
soluble oxazole-based peptide macrocycles that bind selectively to quadruplex DNA, with …
soluble oxazole-based peptide macrocycles that bind selectively to quadruplex DNA, with …
Potent inhibitors of the hepatitis C virus NS3 protease: design and synthesis of macrocyclic substrate-based β-strand mimics
N Goudreau, C Brochu, DR Cameron… - The Journal of …, 2004 - ACS Publications
The virally encoded NS3 protease is essential to the life cycle of the hepatitis C virus (HCV),
an important human pathogen causing chronic hepatitis, cirrhosis of the liver, and …
an important human pathogen causing chronic hepatitis, cirrhosis of the liver, and …
Selective recognition of pyrophosphate in water using a backbone modified cyclic peptide receptor
MJ McDonough, AJ Reynolds, WYG Lee… - Chemical …, 2006 - pubs.rsc.org
Selective recognition of pyrophosphate in water using a backbone modified cyclic peptide
receptor - Chemical Communications (RSC Publishing) DOI:10.1039/B606917G Royal Society of …
receptor - Chemical Communications (RSC Publishing) DOI:10.1039/B606917G Royal Society of …
Selective recognition of sulfate ions by tripodal cyclic peptides functionalised with (thio) urea binding sites
PG Young, KA Jolliffe - Organic & Biomolecular Chemistry, 2012 - pubs.rsc.org
A tripodal urea and tripodal thiourea with the same cyclic peptide core have been
synthesised and their anion binding ability investigated. In CDCl3, the tripodal urea self …
synthesised and their anion binding ability investigated. In CDCl3, the tripodal urea self …
High affinity sulfate binding in aqueous media by cyclic peptides with thiourea arms
VJ Dungan, HT Ngo, PG Young… - Chemical …, 2013 - pubs.rsc.org
High affinity sulfate binding in aqueous media by cyclic peptides with thiourea arms -
Chemical Communications (RSC Publishing) DOI:10.1039/C2CC37686E Royal Society of …
Chemical Communications (RSC Publishing) DOI:10.1039/C2CC37686E Royal Society of …
Hybrid cyclic peptide–thiourea cryptands for anion recognition
Hybrid cyclic peptide – thiourea cryptands for anion recognition - Chemical Communications
(RSC Publishing) DOI:10.1039/C0CC02223C Royal Society of Chemistry View PDF …
(RSC Publishing) DOI:10.1039/C0CC02223C Royal Society of Chemistry View PDF …
Synthesis of a family of cyclic peptide-based anion receptors
We report here the design and synthesis of a family of novel backbone modified cyclic
peptides, bearing dipicolylamine side chains for metal complexation and subsequent anion …
peptides, bearing dipicolylamine side chains for metal complexation and subsequent anion …
Exploring the conformational space of cyclic peptides by a stochastic search method
A stochastic search algorithm is applied in order to probe the conformations of cyclic
peptides. The search is conducted in two stages. In the first stage, random conformations are …
peptides. The search is conducted in two stages. In the first stage, random conformations are …