Cardiac aging is evident by a reduction in function which subsequently contributes to heart
failure. The metabolic microenvironment has been identified as a hallmark of malignancy …

High-density, large-area electronic interfaces are a key component of brain–computer
interface technologies. However, current designs typically require patients to undergo …

Programmable nucleases, such as zinc finger nucleases (ZFNs), transcription activator-like
effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats …

Epithelial cell adhesion molecule (EpCAM) gene encodes a type‐I trans‐membrane
glycoprotein that is overexpressed in many cancerous epithelial cells and promotes tumor …

The enzyme steroid type II 5-alpha-reductase (SRD5α2) is responsible for the conversion of
testosterone to dihydrotestosterone (DHT), which is involved in prostate cancer, benign …

In the past decade, precise targeting through genome editing has emerged as a promising
alternative to traditional therapeutic approaches. Genome editing can be performed using …

The development of nucleic acid‐based drugs holds great promise for therapeutic
applications, but their effective delivery into cells is hindered by poor cellular membrane …

Glypican‐3 (GPC3) is a key diagnostic marker and therapeutic target in hepatocellular
carcinoma (HCC), interacting with Wnt and Hippo/YAP pathways related to cancer …

Necroptosis, a cell death mechanism with the characteristics of both apoptosis and necrosis,
is proposed as a promising therapeutic approach for cancer therapy. Induction of …

Subretinal injection (SR injection) is a commonly used method of ocular drug delivery and
has been mainly applied for the treatment of neovascular age-associated macular …