The synthesis of vitellogenin and its uptake by maturing oocytes during egg maturation are
essential for successful female reproduction. These events are regulated by the juvenile …

Isolation of genes encoding the receptors for steroids, retinoids, vitamin D, and thyroid
hormone and their structural and functional analysis revealed an evolutionarily conserved …

The nuclear receptors REV-ERB (consisting of REV-ERBα and REV-ERBβ) and retinoic acid
receptor-related orphan receptors (RORs; consisting of RORα, RORβ and RORγ) are …

The steroid hormone ecdysone is the central regulator of insect developmental transitions.
Recent new advances in our understanding of ecdysone action have relied heavily on the …

Protoporphyrin IX iron complex (heme) is an important cofactor for oxygen transfer, oxygen
storage, oxygen activation, and electron transfer when bound to the heme proteins …

Insects possess a cuticle that covers all tissues exposed to the outside world including the
body, the fore-and hindgut and the luminal side of the tracheae. The cuticle is a …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

The circadian clock temporally coordinates metabolic homeostasis in mammals. Central to
this is heme, an iron-containing porphyrin that serves as prosthetic group for enzymes …

Blood-feeding insects, including the malaria mosquito Anopheles gambiae, use highly
specialized and sensitive olfactory systems to locate their hosts. This is accomplished by …

The nuclear receptors REV-ERBα (encoded by NR1D1) and REV-ERBβ (NR1D2) have
remained orphans owing to the lack of identified physiological ligands. Here we show that …