Hepatocellular carcinoma: Where are we?

R Mazzanti, U Arena, R Tassi - World journal of experimental …, 2016 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the second cause of death due to malignancy in the
world, following lung cancer. The geographic distribution of this disease accompanies its …

Precision medicine for hepatocellular carcinoma: driver mutations and targeted therapy

XX Ding, QG Zhu, SM Zhang, L Guan, T Li… - …, 2017 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the third most frequent cause of tumor-related mortality
and there are an estimated approximately 850,000 new cases annually. Most HCC patients …

LncRNA FAL1 promotes cell proliferation and migration by acting as a CeRNA of miR-1236 in hepatocellular carcinoma cells

B Li, R Mao, C Liu, W Zhang, Y Tang, Z Guo - Life sciences, 2018 - Elsevier
Abstract Background Long non-coding RNAs (LncRNAs) have been demonstrated to play
crucial role in tumor growth and metastasis for hepatocellular carcinoma (HCC). LncRNA …

MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways

Y Xu, J Huang, L Ma, J Shan, J Shen, Z Yang, L Liu… - Cancer letters, 2016 - Elsevier
Sorafenib is the first-line treatment for advanced hepatocellular carcinoma (HCC), but the
clinical response to sorafenib is seriously limited by drug resistance. In this study, we …

Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma

K Vishnoi, R Ke, N Viswakarma, P Srivastava… - Cell death & …, 2022 - nature.com
The incidence and mortality of hepatocellular carcinoma (HCC) are on a rise in the Western
countries including US, attributed mostly to late detection. Sorafenib has been the first-line …

A NIR ratiometric fluorescent biosensor for sensitive detection and imaging of α‐L‐fucosidase in living cells and HCC tumor‐bearing mice

GQ Zhang, W Feng, Z Gao, GL Zhang, X Wu… - …, 2023 - Wiley Online Library
Detection and imaging of α‐L‐fucosidase (AFU) is of great value to understand its roles in
hepatocellular carcinoma (HCC) and tumor early diagnosis, but ideal assays are still …

Modulation of IGF2BP1 by long non-coding RNA HCG11 suppresses apoptosis of hepatocellular carcinoma cells via MAPK signaling transduction

Y Xu, Y Zheng, H Liu, T Li - … journal of oncology, 2017 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is a common malignancy of the liver. HCG11 is a member
of long non-coding family, upregulation of which in HCC was proved by our previous study …

Berberine upregulates miR-22-3p to suppress hepatocellular carcinoma cell proliferation by targeting Sp1

J Chen, FX Wu, HL Luo, JJ Liu, T Luo… - American journal of …, 2016 - pmc.ncbi.nlm.nih.gov
MicroRNA-22-3p (miR-22-3p) is downregulated in hepatocellular carcinoma (HCC), which
contributes to the development and progression of HCC. In this study, berberine treatment …

Carbon dots and gold nanoparticles based immunoassay for detection of alpha-L-fucosidase

K Mintz, E Waidely, Y Zhou, Z Peng, AO Al-Youbi… - Analytica chimica …, 2018 - Elsevier
Hepatocellular carcinoma (HCC) is among the leading causes of mortality in the world. The
detection of HCC in its early stage is the key for early treatment and thus the improvement of …

A novel microRNAs expression signature for hepatocellular carcinoma diagnosis and prognosis

M Lu, X Kong, H Wang, G Huang, C Ye, Z He - Oncotarget, 2017 - pmc.ncbi.nlm.nih.gov
This study aims to identify prognostic microRNAs (miRNAs) biomarkers for diagnosis and
survival of hepatocellular carcinoma (HCC) based on large patients cohort analysis. HCC …