As a compartment border, the nuclear envelope (NE) needs to serve as both a protective
membrane shell for the genome and a versatile communication interface between the …

Herpesviruses replicate their DNA and package this DNA into capsids in the nucleus. These
capsids then face substantial obstacles to their release from cells. Unlike other DNA viruses …

Herpesvirus particles consist of four morphologically distinct structures, the core, capsid,
tegument, and envelope. The inner nucleoprotein core comprising the linear double …

The herpes simplex virus type 1 (HSV-1) genome is contained in a capsid wrapped by a
complex tegument layer and an external envelope. The poorly defined tegument plays a …

After fusion of the viral envelope with the plasma membrane, herpes simplex virus type 1
(HSV1) capsids are transported along microtubules (MTs) from the cell periphery to the …

The wild-type UL31, UL34, and US3 proteins localized on nuclear membranes and
perinuclear virions; the US3 protein was also on cytoplasmic membranes and extranuclear …

Herpes virions are complex particles that consist of more than 30 different virally encoded
proteins. The molecular basis of how this complicated structure is assembled is only recently …

Vesicle-mediated nucleocytoplasmic transport is a nuclear pore-independent mechanism for
the nuclear export of macromolecular complexes, but the molecular basis for this transport …

ABSTRACT A 2.6-kbp fragment of the pseudorabies virus (PrV) genome was sequenced
and shown to contain the homologues of the highly conserved herpesvirus genes UL31 and …