Highlights•HME can be exploited in a broad range of applications for advanced drug
delivery.•Unique advantages to be utilized in a solvent free manufacturing platform.•A …

Twin-screw melt granulation (TSMG) is a new alternative method for granulation that offers
several advantages over wet and dry granulation methods. TSMG has rapidly gained …

Inhibiting or circumventing drug resistance by using drug delivery systems (DDSs) such as
micelles has attracted significant attention recently. In this present study, a polyvinyl …

The aim of this study was to evaluate the processability of poly (vinyl alcohol)(PVA)-based
filaments containing paracetamol (PAR) prepared by hot-melt extrusion for fused deposition …

Diazepam (DZP) is a long-acting benzodiazepine to treat anxiety or acute alcohol
withdrawal. Although this class of drugs should be taken for a short period of time, many …

Historically, amorphous solid dispersion technology with polymeric carriers has been
employed to stabilize high-energy amorphous phases of poorly water-soluble drug …

In this current article matrix formulations for oral drug delivery are reviewed. Conventional
dosage forms and novel applications such as 3D printed matrices and aerogel matrices are …

The concept of twin-screw melt granulation (TSMG) has steadily (re)-gained interest in
pharmaceutical formulation development as an intermediate step during tablet …

Hydroxypropyl methylcellulose (hypromellose) is a widely known excipient commonly used
in the preparation of drug formulations. It can interact with some active pharmaceutical …

This paper addresses the solid-state and in suspension characterization of the stable
monoclinic form I and the metastable orthorhombic form II of paracetamol via differential …